Results 271 to 280 of about 193,847 (359)

7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome

, 2001
Barbara U. Fitzky, Fabian F. Moebius, Hitoshi Asaoka, Heather Waage-Baudet, Liwen Xu, Guorong Xu, Nobuyo Maeda, Kimberly D. Kluckman, Sylvia Hiller, Hongwei Yu, Ashok K. Batta, Sarah Shefer, Tai C. Chen, Gerald Salen, Kathleen K. Sulik, Robert Simoni, Gene C. Ness, Hartmut Glossmann, Shailendra B. Patel, G. Stephen Tint   +19 more
openalex   +2 more sources

Genome-wide identification and functional validation of sterol C-22 desaturases and C-24 methyltransferases in <i>Asparagus officinalis</i> and <i>Asparagus taliensis</i>. [PDF]

Front Plant Sci
Brown SE, Li Y, Lin C, Liu Z, Mao Z.
europepmc   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

METTL7A inhibits progression of colorectal cancer through the SREBP1 / FDFT1 / SQLE / CYP51A1 / cholesterol metabolic pathway. [PDF]

Cell Oncol (Dordr)
Li S, Chi X, Li X, Li W, Yang H, Cao W, Zhao Y, Zhang X, Meng R, Du G, Zhang D, Wang J.   +11 more
europepmc   +1 more source

Phylogenetic and Structural Analysis of Miconazole Susceptibility in Malassezia pachydermatis Isolates From Dogs With Otitis Externa

Veterinary Dermatology, EarlyView.
ABSTRACT Background An increased number of dogs with unresolved yeast otitis externa (OE) after miconazole treatment was observed at a tertiary practice. Hypothesis/Objectives To evaluate miconazole susceptibility in Malassezia pachydermatis isolates from canine OE.
Cole M. Belcher, Clarissa P. Souza, Elyas McGuire, Chien‐Che Hung, Joel D. A. Tyndall, Lois L. Hoyer   +5 more
wiley   +1 more source

Membrane microdomains are crucial for <i>Mycobacterium marinum</i> EsxA-dependent membrane damage, escape to the cytosol, and infection. [PDF]

Sci Adv
Perret A, Bosmani C, Leuba F, Eblighatian K, Guého A, Raykov L, Hanna N, Soldati T.   +7 more
europepmc   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Coronary artery disease risk and lipidomic profiles are similar in hyperlipidemias with family history and population-ascertained hyperlipidemias [PDF]

, 2019
et al,, Stitziel, Nathan O
core   +1 more source

Short lifespan under dietary cholesterol depletion is associated with gut dysfunction in Drosophila melanogaster females. [PDF]

NPJ Aging
Zanco B, Mirth CK, Sgrò CM, Piper MDW.
europepmc   +1 more source