Results 121 to 130 of about 9,389 (199)

Disruption of the Sterol 27-Hydroxylase Gene in Mice Results in Hepatomegaly and Hypertriglyceridemia [PDF]

Journal of Biological Chemistry, 2000
Joyce J. Repa, Erik G. Lund, Jay D. Horton, Eran Leitersdorf, David W. Russell, John M. Dietschy, Stephen D. Turley   +6 more
openaire   +1 more source

Studies on human sterol 27-hydroxylase with emphasis on its mechanism of regulation and metabolic consequences of a deficient enzyme

, 2007
Sterol 27-hydroxylase (CYP27A1) is a mitochondrial cytochrome P-450 enzyme present in most animal cells. In hepatocytes, CYP27A1 has an important role in connection with biosynthesis of bile acids from cholesterol.
Magnus Hansson (5581217)
core  

Elimination of Cholesterol in Macrophages and Endothelial Cells by the Sterol 27-Hydroxylase Mechanism [PDF]

Journal of Biological Chemistry, 1997
Amir Babiker, Olof Andersson, Erik Lund, Rui-Juan Xiu, Samir Deeb, Ayeleth Reshef, Eran Leitersdorf, Ulf Diczfalusy, Ingemar Björkhem   +8 more
openaire   +1 more source

Studies of sterol 12alpha-hydroxylase (CYP8B1) : distribution and role for cholesterol homeostasis and gallstone formation

, 2006
Bile acids are essential physiological molecules which carry out multiple functions such as facilitating the absorption of dietary lipids and regulating the metabolism of cholesterol and bile acids.
Jin Wang (29560)
core  

Genetic Determinants of Human Serum Sterol Levels

, 2015
Dozens of different cholesterol metabolites are synthesized by mammalian cells and are known to play important physiological roles in the liver, brain, and immune system.
Stiles, Ashlee Renee 1986-
core  

Cerebrotendinous Xanthomatosis: A Reversible Rarity if Caught on Time. [PDF]

Indian Dermatol Online J
Suresh P, Dev PP, Khunger N, Sharma S.
europepmc   +1 more source

Studies on the transcriptional regulation of sterol 12alpha-hydroxylase (CYP8B1)

, 2002
The conversion of cholesterol into bile acids is mainly via two pathways, which are initiated by CYP7A1 and CYP27A1 respectedly. CYP8B1, a microsomal P450 cytochrome, hydroxylates of the steroid nucleus at the C-12alpha position to form 7alpha, 12alpha ...
Yizeng Yang (5683682)
core  

Regulation of sterol metabolism by gut microbiota and its relevance to disease. [PDF]

Gut Microbes
Huang C, Wu Q, Wang J, Cai J, Wang Z, You L, Zhu Z, Ding Y.   +7 more
europepmc   +1 more source

Functional analysis of UDP-sugar: sterol glucosyltransferases

Glycosyltransferases (GTs) are essential for the biosynthesis and diversification of many therapeutically important natural products. Of these, UDP-sugar: sterol glucosyltransferases (UGTs) (2.4.1.173) catalyse the synthesis of therapeutically important ...
Malik, Vatsala
core  

Physiological Functions of Freshwater Clam Extracts and the Exploration of Their Bioactive Compounds. [PDF]

Foods
Kuwano K, Hata M, Umeki M, Mochizuki S, Oda H, Shimazoe T.   +5 more
europepmc   +1 more source