Results 121 to 130 of about 55,660 (196)

Inhibition of the Sterol Regulatory Element Binding Protein SREBF-1 Overcomes Docetaxel Resistance in Advanced Prostate Cancer

The American Journal of Pathology
Resistance to antiandrogens and chemotherapy (Cx) limits therapeutic options for patients with metastatic hormone-sensitive (mHSPC) and metastatic castration-resistant (mCRPC) prostate cancer. In this context, up-regulation of the glucocorticoid receptor is identified as a potential bypass mechanism in mCRPC. A combination of docetaxel and mifepristone
Maximilian P. Brandt, Olesya Vakhrusheva, Hubert Hackl, Tamas Daher, Katrin Tagscherer, Wilfried Roth, Igor Tsaur, Florian Handle, Andrea Eigentler, Zoran Culig, Christian Thomas, Holger H.H. Erb, Axel Haferkamp, Eva Jüngel, Martin Puhr   +14 more
openaire   +3 more sources

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice
MicroRNAs (miRs) are small non-protein-coding RNAs that bind to specific mRNAs and inhibit translation or promote mRNA degradation. Recent reports have indicated that miR-33, which is located within the intron of sterol regulatory element-binding protein (SREBP) 2, controls cholesterol homoeostasis and may be a potential therapeutic target for the ...
openaire   +1 more source

SREBP-2, a new target of metformin?

Drug Design, Development and Therapy, 2018
Fengxia Zhang,1,* Wenxiu Sun,2,* Jianbo Chen,3 Lusheng Jiang,3 Ping Yang,3 Yufang Huang,3 Aihua Gong,3 Shudong Liu,3 Shizhan Ma4 1Department of Neurology, Affiliated Hospital of Shandong Traditional Chinese Medicine University, Jinan 250011, China ...
Zhang F, Sun W, Chen J, Jiang L, Yang P, Huang Y, Gong A, Liu S, Ma S   +8 more
doaj  

Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae. [PDF]

, 2019
The evolutionarily conserved Target of Rapamycin (TOR) complex-2 (TORC2) is an essential regulator of plasma membrane homeostasis in budding yeast (Saccharomyces cerevisiae).
Locke, Melissa N, Thorner, Jeremy
core   +1 more source

Sterol regulatory element-binding protein 1 cooperates with c-Myc to promote epithelial-mesenchymal transition in colorectal cancer. [PDF]

Oncol Lett, 2018
Zhai D, Cui C, Xie L, Cai L, Yu J.
europepmc   +1 more source

Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma. [PDF]

J Pathol, 2018
Lo AK, Lung RW, Dawson CW, Young LS, Ko CW, Yeung WW, Kang W, To KF, Lo KW.   +8 more
europepmc   +1 more source

Sterol Regulatory Element Binding Protein-1 Expression Is Suppressed by Dietary Polyunsaturated Fatty Acids [PDF]

Journal of Biological Chemistry, 1999
Jing Xu, Manabu T. Nakamura, Hyekyung P. Cho, Steven D. Clarke   +3 more
openaire   +1 more source

Eicosapentaenoic Acid Improves Polycystic Ovary Syndrome in Rats via Sterol Regulatory Element-Binding Protein 1 (SREBP-1)/Toll-Like Receptor 4 (TLR4) Pathway. [PDF]

Med Sci Monit, 2018
Wang Y, He J, Yang J.
europepmc   +1 more source

0868 Regulation of sterol regulatory element binding protein-1 in bovine mammary epithelial cells [PDF]

Journal of Animal Science, 2016
L. Chen, B. A. Corl
openaire   +1 more source

Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice-Potential Link to Cognitive Impairment in Schizophrenia. [PDF]

Mol Neurobiol, 2017
Chen Y, Bang S, McMullen MF, Kazi H, Talbot K, Ho MX, Carlson G, Arnold SE, Ong WY, Kim SF.   +9 more
europepmc   +1 more source