Results 71 to 80 of about 55,660 (196)

Effects of sterol regulatory element-binding protein (SREBP) in chickens

open access: yesLipids in Health and Disease, 2012
Sterol regulatory element binding protein- 1 and -2 (SREBP-1 and -2) are key transcription factors involved in the biosynthesis of cholesterol and fatty acids.
Alipour Fahimeh, Hassanabadi Ahmad
doaj   +1 more source

Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel

open access: yesLipids in Health and Disease, 2023
Background Curcumin (Cur) is a bioactive dietary polyphenol of turmeric with various biological activities against several cancers. Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths.
Si Qin   +7 more
doaj   +1 more source

Trifuhalol A, a phlorotannin from the brown algae Agarum cribrosum, reduces adipogenesis of human primary adipocytes through Wnt/β-catenin and AMPK-dependent pathways

open access: yesCurrent Research in Food Science, 2023
Trifuhalol A, a fucol-type phlorotannin, was extracted and identified from the brown algae Agarum cribrosum. The total yield and purity of trifuhalol A from A. cribrosum were 0.98% and 86%, respectively.
Aaron Taehwan Kim, Yeonhwa Park
doaj   +1 more source

An examination of the molecular mechanisms controlling the tissue accumulation of conjugated linoleic acid (CLA) in cattle [PDF]

open access: yes, 2008
End of project reportLong chain n-3 polyunsaturated fatty acids (n-3 PUFA) and conjugated linoleic acid (CLA) have demonstrable and potential human health benefits in terms of preventing cancer, diabetes, chronic inflammation, obesity and coronary heart ...
Hynes, A.C.   +4 more
core  

The compositional and metabolic responses of gilthead seabream (Sparus aurata) to a gradient of dietary fish oil and associated n-3 long-chain PUFA content [PDF]

open access: yes, 2017
The authors express their gratitude to the technical team at the BioMar Feed Trial Unit, Hirtshals, in particular, Svend Jørgen Steenfeldt for expert care of the experimental subjects, for training and supervision provided by laboratory staff at ...
Betancor, Mónica B   +6 more
core   +2 more sources

Oxysterols and Their Cellular Effectors [PDF]

open access: yes, 2012
Oxysterols are oxidized 27-carbon cholesterol derivatives or by-products of cholesterol biosynthesis, with a spectrum of biologic activities. Several oxysterols have cytotoxic and pro-apoptotic activities, the ability to interfere with the lateral domain
Béaslas, Olivier   +2 more
core   +3 more sources

Secreted Site-1 Protease Cleaves Peptides Corresponding to Luminal Loop of Sterol Regulatory Element-binding Proteins [PDF]

open access: yesJournal of Biological Chemistry, 1999
We describe a permanent line of Chinese hamster ovary cells transfected with a cDNA encoding a truncated form of Site-1 protease (S1P) that is secreted into the culture medium in an enzymatically active form. S1P, a subtilisin-like protease, normally cleaves the luminal loop of sterol regulatory element-binding proteins (SREBPs).
D, Cheng   +5 more
openaire   +2 more sources

Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver

open access: yesJournal of Lipid Research, 2011
Orotic acid (OA), an intermediate in pyrimidine metabolism, has been used for a variety of purposes, such as dietary supplements. Although it is well documented that OA induces fatty liver in a species-specific manner, the precise molecular mechanisms ...
Eun-Jeong Jung   +4 more
doaj   +1 more source

Euglena extract suppresses adipocyte-differentiation in human adipose-derived stem cells. [PDF]

open access: yesPLoS ONE, 2018
Euglena gracilis Z (Euglena) is a unicellular, photosynthesizing, microscopic green alga. It contains several nutrients such as vitamins, minerals, and unsaturated fatty acids.
Ryota Sugimoto   +6 more
doaj   +1 more source

Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. [PDF]

open access: yes, 2014
Glycogen and lipids are major storage forms of energy that are tightly regulated by hormones and metabolic signals. We demonstrate that feeding mice a high-fat diet (HFD) increases hepatic glycogen due to increased expression of the glycogenic ...
Bridges, Dave   +12 more
core   +2 more sources

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