Results 101 to 110 of about 115,731 (294)

Ultrastructural characterization (morphological and topochemical) of wood pulp fibres [PDF]

open access: yes, 2007
Different electron microscopy techniques including SEM (scanning electron microscopy), FE-SEM (field emission-scanning electron microscopy), TEM (transmission electron microscopy) and Immuno-gold TEM (immuno-gold transmission electron microscopy) were ...
Fernando, Dinesh
core  

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

open access: yes, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping   +8 more
core   +1 more source

Traceless Regulation of Genetic Circuitry

open access: yesAdvanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Traditional herbal medicines: potential degradation of sterols and sterolins by microbial contaminants

open access: yesSouth African Journal of Science, 2009
Medicinal plants with a high content of sterols and sterolins, such as Bulbine natalensis (rooiwortel) and Hypoxis hemerocallidea (African potato), are commonly and inappropriately used in South Africa for the treatment of HIV/AIDS due to the ...
D. du Plessis-Stoman   +3 more
doaj  

Paleoproterozic Icehouses and the Evolution of Oxygen Mediating Enzymes: The Case for a Late Origin of Photosystem -- II [PDF]

open access: yes, 2008
Two major geological problems regarding the origin of oxygenic photosynthesis are: (1) identifying a source of oxygen predating biological oxygen production and capable of driving the evolution of oxygen tolerance, and (2) determining when oxygenic ...
Kirschvink, Joseph L., Kopp, Robert E.
core  

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]

open access: yes, 2010
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
core   +1 more source

The microstratigraphy of middens: capturing daily routine in rubbish at Neolithic Çatalhöyük, Turkey [PDF]

open access: yes, 2011
Microstratigraphy — the sequencing of detailed biological signals on site — is an important new approach being developed in the Çatalhöyük project. Here the authors show how microscopic recording of the strata and content of widespread middens on the ...
Almond, Matthew J.   +3 more
core   +1 more source

Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee   +3 more
wiley   +1 more source

Evaluation of the methods based on triglycerides and sterols for the detection of hazelnut oil in olive oil

open access: yesGrasas y Aceites, 2007
Two analytical methods, based on the difference between theoretical and empirical triglycerides and the ratios between some free and esterified sterols have been checked to determine their usefulness in detecting the presence of low quantities of any ...
Diego L. García-González   +3 more
doaj   +1 more source

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