Results 191 to 200 of about 115,811 (342)

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová   +12 more
wiley   +1 more source

Breaking the Boring Billion

open access: yesGeophysical Monograph Series, Page 487-501., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Charles W. Diamond   +3 more
wiley  

+1 more source

Unveiling belowground allelopathy: <sup>1</sup>H-NMR spectroscopy reveals metabolic crosstalk and novel sterols in <i>Cyperus rotundus</i> and <i>Sorghum bicolor</i> co-cultures. [PDF]

open access: yesFront Plant Sci
Giorgi G   +12 more
europepmc   +1 more source

The Genetic Landscape of Hereditary Spastic Paraplegia in Greece

open access: yesClinical Genetics, EarlyView.
We investigated 112 Greek index‐cases with hereditary spastic paraplegia collected over > 25 years using NGS and MLPA. We identified a causative variant in 68 patients (60.7%), including 7 novel causative variants. This study presents a comprehensive overview of the phenotypic and genotypic spectrum of HSP in the Greek population.
Georgios Koutsis   +19 more
wiley   +1 more source

To Avoid or Not to Avoid: Cross‐Reactivity Between Fragrance and Common Botanicals

open access: yesContact Dermatitis, EarlyView.
Among 356 fragrance‐allergic patients patch tested from 2020–2024, no clinically meaningful cross‐reactivity (> 10%) was observed between fragrance allergens and common non‐essential oil botanicals. These findings suggest fragrance‐allergic patients do not need to avoid botanicals such as aloe, coconut oil, or shea butter in fragrance‐free products ...
Sarah Karels   +5 more
wiley   +1 more source

Metabolomic Analysis of Phytophthora parasitica Growth in the Presence of β-sitosterol Indicates Adaptive Mechanisms Modulated by Sterols. [PDF]

open access: yesJ Basic Microbiol
Martins PP   +7 more
europepmc   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

open access: yesCell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy