Results 11 to 20 of about 461 (139)
Treatment of Radiation‐Induced Brain Necrosis
Oxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021 Radiation‐induced brain necrosis (RBN) is a serious complication of intracranial as well as skull base tumors after radiotherapy. In the past, due to the lack of effective treatment, radiation brain necrosis was considered to be progressive and irreversible. With better understanding in histopathology and neuroimaging, the occurrence and development of
Xiaojing Yang +3 more
wiley +1 more source
Stichodactyla helianthus' de novo transcriptome assembly: Discovery of a new actinoporin isoform [PDF]
Toxicon, 2018 Transcriptomic profiling of venom producing tissues from different animals is an effective approach for discovering new toxins useful in biotechnological and pharmaceutical applications, as well in evolutionary comparative studies of venomous animals. Stichodactyla helianthus is a Caribbean sea anemone which produces actinoporins as part of its toxic ...
Esperanza Rivera-de-Torre +2 more
openaire +3 more sources
Frontiers in Neuroscience, 2020 It remains a challenge for the effective treatment of neuroinflammatory disease, including multiple sclerosis (MS), stroke, epilepsy, and Alzheimer’s and Parkinson’s disease.
Xiaoli Wang +12 more
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Toxins, 2021 Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that experience conformational changes originating in pores in the membranes that can lead to cell death. The processes involved in the binding and pore-formation of members of
Carlos Alvarez +8 more
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Determination of the boundary lipids of sticholysins using tryptophan quenching
Scientific Reports, 2022 Sticholysins are α-pore-forming toxins produced by the sea-anemone Stichodactyla helianthus. These toxins exert their activity by forming pores on sphingomyelin-containing membranes.
Juan Palacios-Ortega +7 more
doaj +1 more source
Ecology and Evolution, Volume 10, Issue 21, Page 12348-12363, November 2020., 2020 We investigated the abundance and gene expression of scavenger receptors and thrombospondin‐type‐1 repeat protein superfamily, known to be involved in symbiont recognition, in three plastid‐bearing sea slugs. We could identify candidate receptors, similar to those found in cnidarians for Symbiodinium recognition, that might be relevant in plastid ...
Jenny Melo Clavijo +6 more
wiley +1 more source
Journal of Venomous Animals and Toxins including Tropical Diseases, 2018 Background Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities.
Cláudia S. Oliveira +13 more
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Functional characterization of sticholysin I and W111C mutant reveals the sequence of the actinoporin's pore assembly. [PDF]
PLoS ONE, 2014 The use of pore-forming toxins in the construction of immunotoxins against tumour cells is an alternative for cancer therapy. In this protein family one of the most potent toxins are the actinoporins, cytolysins from sea anemones.
Valeria Antonini +6 more
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Revista de Investigaciones Marinas, 2023 Sticholisina II (St II) es una citolisina aislada de la anémona marina Stichodactyla helianthus. Esta proteína hidrofilica forma poros en las membranas celulares, lo que provoca el desbalance osmótico que conduce a la lisis celular.
Ariel Basulto Perdomo +3 more
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ZooKeys, 2014 Caridean shrimps are a highly diverse group and many species form symbiotic relationships with different marine invertebrates. Periclimenes rathbunae is a brightly colored shrimp that lives predominantly in association with sea anemones.
Juan Carlos Azofeifa-Solano +2 more
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