Anti-diabetic Potential of a Stigmasterol From the Seaweed Gelidium spinosum and Its Application in the Formulation of Nanoemulsion Conjugate for the Development of Functional Biscuits [PDF]
Frontiers in Nutrition, 2021 The seaweed Gelidium spinosum was selected for the extraction of phytosterol by the Soxhlet method. The extracted phytosterol was chemically characterized as stigmasterol using Fourier-transform infrared spectrometry and gas chromatography–mass ...
Navya Poulose +6 more
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Structure and Properties of Organogels Prepared from Rapeseed Oil with Stigmasterol [PDF]
Foods, 2022 This work used the natural ingredient stigmasterol as an oleogelator to explore the effect of concentration on the properties of organogels. Organogels based on rapeseed oil were investigated using various techniques (oil binding capacity, rheology ...
Caili Tang +10 more
doaj +2 more sources
Analysis of phytosterols encapsulated in pegylated liposomes [PDF]
Scientific ReportsDipalmitoylphosphatidylcholine (DPPC) lipids were encapsulated in PEGylated liposomes with free stigmasterol (ST), stigmasterol myristate (ME), and stigmasterol oleate (OE).
Joanna Igielska-Kalwat +6 more
doaj +2 more sources
SBT (Composed of Panax ginseng and Aconitum carmichaeli) and Stigmasterol Enhances Nitric Oxide Production and Exerts Curative Properties as a Potential Anti-Oxidant and Immunity-Enhancing Agent [PDF]
Antioxidants, 2022 Immune dysregulation is a risk factor for several diseases, including infectious diseases. Immunostimulatory agents have been used for the treatment of immune dysregulation, but deleterious adverse effects have been reported.
Na-Ra Han +5 more
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Stigmasterol Protects Against Dexamethasone-Induced Muscle Atrophy by Modulating the FoxO3–MuRF1/MAFbx Signaling Pathway in C2C12 Myotubes and Mouse Skeletal Muscle [PDF]
BiomoleculesGlucocorticoid therapy, using agents like dexamethasone (Dexa), often leads to muscle atrophy by increasing protein degradation via the ubiquitin–proteasome system while suppressing protein synthesis. Stigmasterol, a phytosterol with known bioactivities,
Young-Sool Hah +7 more
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Research Progress on the Therapeutic Mechanisms of Stigmasterol for Multiple Diseases [PDF]
MoleculesStigmasterol is a plant-derived phytosterol that has attracted considerable attention because of its diverse biological activities and potential therapeutic applications.
Juan Li, Xinhua Zheng, Jinxu Qi
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Effect of gastrointestinal digestion on the stability and cytotoxicity of conventional and pegylated liposomes encapsulated with stigmasterol and its esters [PDF]
Scientific ReportsConventional and PEGylated liposomes encapsulated with stigmasterol and its esters were prepared, and their stability and cytotoxicity during in vitro gastrointestinal digestion were determined. The release of stigmasterol and its oxidation products were
Magdalena Rudzińska +6 more
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Stigmasterol Decreases Oncostatin M Production Through Suppressing PI3K/Akt/NF-κB Signaling Processes in Neutrophil-like Differentiated HL-60 Cells [PDF]
BiomedicinesBackground: Cytokine oncostatin M (OSM) is implicated in inflammatory conditions. The plant sterol stigmasterol (ST) is found in diverse plant foods and exerts various benefits, such as antitumor, antioxidant, and anti-inflammatory effects.
Na-Ra Han +3 more
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Exploring the antidepressant-like effect of stigmasterol using network pharmacology with molecular docking and in vivo experimental validation. [PDF]
Sci RepBiney RP +7 more
europepmc +3 more sources
Pharmaceutical Biology, 2023 Context Stigmasterol has significant anti-arthritis and anti-inflammatory effects, but its role in immune and inflammatory diseases is still unclear.Objective The potential advantages of stigmasterol in asthma were explored in IL-13-induced BEAS-2B cells
Jimei Zhang +5 more
doaj +1 more source