Results 101 to 110 of about 31,588 (256)

Isolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of DMBA-induced skin carcinoma

Drug Design, Development and Therapy, 2015
Huma Ali,1 Savita Dixit,1 Daoud Ali,2 Saeed M Alqahtani,3 Saad Alkahtani,2 Saud Alarifi2 1Department of Chemistry, Maulana Azad National Institute of Technology, Bhopal, India; 2Department of Zoology, College of Science, King Saud University, Riyadh ...
Ali H, Dixit S, Ali D, Alqahtani SM, Alkahtani S, Alarifi S   +5 more
doaj  

Investigating the Chemical, Antifungal, and Cytotoxic Properties of Cochlospermum vitifolium Leaves and Stem Bark Extracts

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
This figure contains images created by Freepik from Flaticon. ABSTRACT Comprehensive analysis of the chemical properties and bioactivities of plant extracts is essential for identifying compounds with therapeutic potential. This study analyzed hydroethanolic extracts from the leaves and stem bark of Cochlospermum vitifolium, investigating their ...
Francisco A. S. D. Pinheiro, Addison R. Almeida, Matheus S. Menezes, Thomaz Rocha, Weslley S. Paiva, Hugo A. O. Rocha, Cristiane F. de Assis, Gislene Ganade, Laila S. Espindola, Leandro S. Ferreira   +9 more
wiley   +1 more source

Erythroside: A New Cerebroside and Other Compounds From Erythrina Caffra Thunb. (Fabaceae) Stem Bark, With Cytotoxicity and Antioxidant Evaluation [PDF]

Chem Biodivers
ABSTRACT The chemical investigation of a CH2Cl2:MeOH (1:1) extract of the stem bark of Erythrina caffra resulted in the isolation and characterisation of the novel cerebroside, erythroside (1), alongside eight other known compounds (2‐9). The isolated compounds were characterized by FT‐IR, 1D and 2D NMR spectroscopy, and ESI‐MS analysis.
Tsakem B, Serem J, Hlophe Y, Kamdem Kengne M, Sandjo L, Ndinteh D, Teponno R, Ambele M, Siwe Noundou X.   +8 more
europepmc   +2 more sources

Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma [PDF]

, 2011
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxygenase activity.
Vipin Bulani, Kailash Biyani, Ravindra Kale, Unmesh Joshi, Kishor Charhate, Dinesh Kumar, Ramesh Pagore, Int J Cur Bio Med Sci.
core  

Valorization of Banana Biomass: Nutritional and Phytochemical Insights With Applications in Food and Allied Industries

eFood, Volume 7, Issue 2, April 2026.
Composition, biological activity and food application of banana biomass. ABSTRACT The global banana processing industry generates substantial organic waste in the form of peels, leaves, stems, and flowers, posing both environmental challenges and opportunities for valorization within a circular economy framework.
Bushra Iram Fatima, Saeed Akhtar, Muhammad Zulqarnain Khan, Muhammad Qamar, Tariq Ismail, Wisha Saeed, Elham Assadpour, Tuba Esatbeyoglu, Seid Mahdi Jafari   +8 more
wiley   +1 more source

Antimalarial Evaluation of the Chemical Constituents of Hairy Root Culture of Bixa orellana L.

Molecules, 2014
Over 216 million malaria cases are reported annually worldwide and about a third of these cases, primarily children under the age of five years old, will not survive the infection.
Bo Zhai, Julie Clark, Taotao Ling, Michele Connelly, Fabricio Medina-Bolivar, Fatima Rivas   +5 more
doaj   +1 more source

The potential LXRβ agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons.

Phytomedicine, 2020
BACKGROUND Neuronal excitotoxicity induces a plethora of downstream signaling pathways, resulting in the calcium overload-induced excitotoxic cell death, a well-known phenomenon in cerebrovascular and neurodegenerative disorders.
Md. Nazmul Haque, M. Hannan, R. Dash, S. Choi, I. Moon   +4 more
semanticscholar   +1 more source

Multifaceted Evaluation of Syngonium podophyllum Flower Extracts: Anthelmintic, Antidiabetic, Antipyretic, and Antidiarrheal Potentials via Experimental, In Silico, and DFT Approaches

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
The methanolic extract of Syngonium podophyllum flower demonstrated significant anthelmintic, antidiabetic, antidiarrheal, and antipyretic effects across all in vitro and in vivo experimental models. Furthermore, in silico studies revealed that these phytoconstituents exhibit favorable pharmacokinetic properties, interact with key therapeutic target ...
Mahathir Mohammad, Nusrat Jahan Moon, Md. Hossain Rasel, Md. Anisul Islam, Nazmul Hasan Eshaque, Md. Jahirul Islam Mamun, Md. Zamil Hossain, Md. Mahmudul Hasan, Md. Tanvir Chowdhury, S. M. Moazzem Hossen   +9 more
wiley   +1 more source

A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome

Journal of Lipid Research
Disease-specific sterols accumulate in the blood of patients with several rare lipid disorders. Biochemical measurement of these sterols is important for correct diagnosis and sometimes monitoring of treatment.
Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl   +8 more
doaj   +1 more source

Stigmasterol sensitizes endometrial cancer cells to chemotherapy by repressing Nrf2 signal pathway

Cancer Cell International, 2020
Background Chemoresistance reduces the 5-year survival rate of endometrial cancer patient, which is the current major obstacle for cancer therapy. Increasing evidence state that Nrf2 contributes to chemoresistance in several kinds of cancer. However, its
H. Liao, Dan Zhu, Mingzhu Bai, Huifen Chen, shi-Jie Yan, Jing Y. Yu, Huiting Zhu, Wenxin Zheng, G. Fan   +8 more
semanticscholar   +1 more source