Results 81 to 90 of about 15,568 (207)

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng   +7 more
wiley   +1 more source

Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments

open access: yesFrontiers in Pharmacology
IntroductionAcute pancreatitis (AP) is a severe inflammatory disease of the pancreas that could trigger a systemic inflammation and multi-organ dysfunction.
Xuanlin Zhao   +8 more
doaj   +1 more source

Cytotoxic furanosesquiterpenoids and steroids from Ircinia mutans sponges

open access: yesPharmaceutical Biology, 2021
Context Ircinia mutans Wilson (Irciniidae) is a sponge with antimicrobial and cytotoxic constituents. Objective Our objective was to characterise the cytotoxic constituents of two seasonal collections of I. mutans.
Fatemeh Heidary Jamebozorgi   +8 more
doaj   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

open access: yesPhytotherapy Research, Volume 40, Issue 10, Page 6005-6042, October 2026.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen   +4 more
wiley   +1 more source

HPTLC method development and validation of stigmasterol from different extracts of Tagetes erecta and Capsicum annuum [PDF]

open access: yes, 2019
A new, simple, sensitive, selective, precise and robust high-performance thin-layer chromatographic (HPTLC) method for analysis of stigmasterol was developed and validated for the determination of stigmasterol in different extracts.
Padole, Aishwarya S.   +2 more
core   +1 more source

Avaliação do potencial alelopático de substâncias isoladas em sementes de araticum (Annona crassiflora) Allelophatic potential of substances isolated from Annona crassiflora seeds

open access: yesPlanta Daninha, 2010
Este estudo visou identificar substâncias biologicamente ativas e o potencial alelopático de esteroides glicosilados, provenientes das sementes de Annona crassiflora.
M.H Inoue   +7 more
doaj   +1 more source

Steroids from Poison Hemlock (Conium maculatum L.): A GC-MS analysis [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
The steroid content of Conium maculatum L. (Poison Hemlock), Apiaceae, a well-known weed plant species, was studied herein for the first time. This was achieved by detailed GC-MS analyses of twenty two samples (dichloromethane extracts of different ...
Radulović Niko S.   +1 more
doaj   +1 more source

Eriosema glomeratum Possessed Interesting Bioactive Constituents and Semisynthetic Derivatives With Relevant Biosynthetic Correlation and Important Chemophenetic Significance

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A medicinal plant Eriosema glomeratum has potentially lead compounds, erioschalcones A and B, and their semisynthetic derivatives for drug discovery. ABSTRACT Plants are sources of compounds with benefits in human health and animal well‐being. Plant‐based foods may contain huge numbers of different phytochemicals.
Gaétan Tchangou Tabakam   +1 more
wiley   +1 more source

Effect of stigmasterol on lipopolysaccharide-induced neuroinflammation in mice [PDF]

open access: yes, 2017
Neuroinflammation is the combination of the responses of all cells in the CNS. The long term regulation of inflammation can cause degeneration of neurons which lead to neurodegenerative disease such as Alzheimer's disease and Parkinson's disease.
Zainal Azwan, Siti Nor Amirah
core  

Determination of stigmasterol hydroperoxides using high-performance liquid chromatography-mass spectrometry with atmospheric pressure chemical ionization

open access: yesCzech Journal of Food Sciences, 2004
A new specific method using high-performance liquid chromatography-mass spectrometry (HPLC-MS) for the detection of stigmasterol hydroperoxides was developed.
S. Kemmo   +3 more
doaj   +1 more source

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