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Health Benefits and Pharmacological Properties of Stigmasterol
Antioxidants, 2022 Stigmasterol is an unsaturated phytosterol belonging to the class of tetracyclic triterpenes. It is one of the most common plant sterols, found in a variety of natural sources, including vegetable fats or oils from many plants.
Saad Bakrim +9 more
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Zhongguo youzhi, 2022 为了探究脂肪酸饱和度对其植物甾醇酯生物可给率的影响，采用体外模拟消化静态模型，系统研究了油酸豆甾醇酯、亚油酸豆甾醇酯和亚麻酸豆甾醇酯的体外模拟消化规律。结果表明：体外模拟消化结束后（120 min),亚油酸豆甾醇酯游离脂肪酸（FFA）释放率最高，为78.51%，其次是亚麻酸豆甾醇酯，为74.21%，油酸豆甾醇酯FFA释放率最低，为69.15%；3种豆甾醇酯的水解速率由大到小为亚麻酸豆甾醇酯>亚油酸豆甾醇酯>油酸豆甾醇酯；3种豆甾醇酯的水解度由大到小为亚油酸豆甾醇酯>亚麻酸豆甾醇酯>油酸豆甾醇酯 ...
王涛1，刘睿杰1，王艳军2，王兴国1，常明1WANG Tao1, LIU Ruijie1, WANG Yanjun2, WANG Xingguo1, CHANG Ming1
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Maize Zmcyp710a8 Mutant as a Tool to Decipher the Function of Stigmasterol in Plant Metabolism
Frontiers in Plant Science, 2021 Sterols are integral components of membrane lipid bilayers in eukaryotic organisms and serve as precursors to steroid hormones in vertebrates and brassinosteroids (BR) in plants.
Siddique I. Aboobucker +3 more
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Advances in Stigmasterol on its anti-tumor effect and mechanism of action
Frontiers in Oncology, 2022 Stigmasterol is a phytosterol derived from multiple herbaceous plants such as herbs, soybean and tobacco, and it has received much attention for its various pharmacological effects including anti-inflammation, anti-diabetes, anti-oxidization, and ...
Xiaoyu Zhang +6 more
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In vitro cytotoxic effect of stigmasterol derivatives against breast cancer cells
BMC Complementary Medicine and Therapies, 2023 Background Stigmasterol is an unsaturated phytosterol that belong to the class of tetracyclic steroids abundant in Rhoicissus tridentata. Stigmasterol is an important constituent since it has shown impressive pharmacological effects such as anti ...
Nondumiso Premilla Dube +8 more
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Frontiers in Immunology, 2021 Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with gut microbiota disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol, a plant-derived sterol, has shown anti-inflammatory effects. Our study aimed
Shuting Wen +8 more
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Pharmaceutics, 2020 Background: Phytosterols have physiological effects and are used as medicines or food supplements. Stigmasterol has shown anticancer effects against various cancers such as hepatoma, cholangiocarcinoma, gall bladder carcinoma, endometrial adenocarcinoma ...
Hyocheol Bae, Gwonhwa Song, Whasun Lim
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Comparative effects of dietary stigmasterol and oxidised stigmasterol on cholesterol absorption and metabolism in mice. [PDF]
Br J NutrAbstract Dietary phytosterols exert hypocholesterolemic effects by inhibiting cholesterol absorption in the small intestine. However, oxidised phytosterols exert harmful effects. In this study, we compared the effects of dietary stigmasterol or oxidised stigmasterol (OS) on cholesterol absorption and metabolism in
Ohara Y, Osada K.
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Cytotoxic furanosesquiterpenoids and steroids from Ircinia mutans sponges
Pharmaceutical Biology, 2021 Context Ircinia mutans Wilson (Irciniidae) is a sponge with antimicrobial and cytotoxic constituents. Objective Our objective was to characterise the cytotoxic constituents of two seasonal collections of I. mutans.
Fatemeh Heidary Jamebozorgi +8 more
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