Results 11 to 20 of about 31,144 (246)
Research Progress on the Therapeutic Mechanisms of Stigmasterol for Multiple Diseases
Stigmasterol is a plant-derived phytosterol that has attracted considerable attention because of its diverse biological activities and potential therapeutic applications.
Juan Li, Xinhua Zheng, Jinxu Qi
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Analysis of phytosterols encapsulated in pegylated liposomes [PDF]
Dipalmitoylphosphatidylcholine (DPPC) lipids were encapsulated in PEGylated liposomes with free stigmasterol (ST), stigmasterol myristate (ME), and stigmasterol oleate (OE).
Joanna Igielska-Kalwat +6 more
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Stigmasterol Protects Against Dexamethasone-Induced Muscle Atrophy by Modulating the FoxO3–MuRF1/MAFbx Signaling Pathway in C2C12 Myotubes and Mouse Skeletal Muscle [PDF]
Glucocorticoid therapy, using agents like dexamethasone (Dexa), often leads to muscle atrophy by increasing protein degradation via the ubiquitin–proteasome system while suppressing protein synthesis. Stigmasterol, a phytosterol with known bioactivities,
Young-Sool Hah +7 more
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Why Do Plants Convert Sitosterol to Stigmasterol?
A direct role for cholesterol signaling in mammals is clearly established; yet, the direct role in signaling for a plant sterol or sterol precursor is unclear.
Siddique I. Aboobucker, Walter P. Suza
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Stigmasterol Decreases Oncostatin M Production Through Suppressing PI3K/Akt/NF-κB Signaling Processes in Neutrophil-like Differentiated HL-60 Cells [PDF]
Background: Cytokine oncostatin M (OSM) is implicated in inflammatory conditions. The plant sterol stigmasterol (ST) is found in diverse plant foods and exerts various benefits, such as antitumor, antioxidant, and anti-inflammatory effects.
Na-Ra Han +3 more
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为了探究脂肪酸饱和度对其植物甾醇酯生物可给率的影响,采用体外模拟消化静态模型,系统研究了油酸豆甾醇酯、亚油酸豆甾醇酯和亚麻酸豆甾醇酯的体外模拟消化规律。结果表明:体外模拟消化结束后(120 min),亚油酸豆甾醇酯游离脂肪酸(FFA)释放率最高,为78.51%,其次是亚麻酸豆甾醇酯,为74.21%,油酸豆甾醇酯FFA释放率最低,为69.15%;3种豆甾醇酯的水解速率由大到小为亚麻酸豆甾醇酯>亚油酸豆甾醇酯>油酸豆甾醇酯;3种豆甾醇酯的水解度由大到小为亚油酸豆甾醇酯>亚麻酸豆甾醇酯>油酸豆甾醇酯 ...
王涛1,刘睿杰1,王艳军2,王兴国1,常明1WANG Tao1, LIU Ruijie1, WANG Yanjun2, WANG Xingguo1, CHANG Ming1
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Insilico study of stigmasterol extracted from pluchea indica as antiferility in men [PDF]
Docking is a method to predict the strength of the interaction between the receptor and the ligand based on the binding affinity value. The docking carried out in this study is a specific docking with a grid box imitating the bond between AR and ...
Fatmawati, Diani +4 more
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Maize Zmcyp710a8 Mutant as a Tool to Decipher the Function of Stigmasterol in Plant Metabolism
Sterols are integral components of membrane lipid bilayers in eukaryotic organisms and serve as precursors to steroid hormones in vertebrates and brassinosteroids (BR) in plants.
Siddique I. Aboobucker +3 more
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Drought stress is an unavoidable challenge limiting plant production and quality. Stigmasterol is a potential compound for plant protection and improvement productivity under drought.
R. S. Hanafy, M. S. Sadak
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BACKGROUND Hepatic cholesterol accumulation is a significant risk factor in the progression of non-alcoholic fatty liver disease (NAFLD) to steatohepatitis.
Yan Xin +7 more
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