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Stigmasterol hemihydrate

Acta Crystallographica Section C Crystal Structure Communications, 2002
The title compound, stigmasta-5,22-dien-3beta-ol hemihydrate, C(29)H(48)O x 0.5H(2)O, previously thought to be the monohydrate, has two sterol molecules and one water molecule in the asymmetric unit. In both sterol molecules, the methyl group of the ethyl substituent at the end of the hydrocarbon chain is disordered over two sites.
Gloria A, Benavides   +2 more
openaire   +2 more sources

Stigmasterol isolated from Azadirachta indica flowers attenuated glutamate-induced neurotoxicity via downregulation of the Cdk5/p35/p25 signaling pathway in the HT-22 cells.

Phytomedicine, 2023
BACKGROUND Glutamate, an excitatory neurotransmitter, was elevated in the brain of neurodegenerative disease (ND) patients. The excessive glutamate induces Ca2+ influx and reactive oxygen species (ROS) production which exacerbates mitochondrial function,
K. Mongkolpobsin   +4 more
semanticscholar   +1 more source

Stigmasterol protects human brain microvessel endothelial cells against ischemia-reperfusion injury through suppressing EPHA2 phosphorylation.

Chinese Journal of Natural Medicines, 2023
Stigmasterol is a plant sterol with anti-apoptotic, anti-oxidative and anti-inflammatory effect through multiple mechanisms. In this study, we further assessed whether it exerts protective effect on human brain microvessel endothelial cells (HBMECs ...
Supin Li   +5 more
semanticscholar   +1 more source

Polyamine conjugates of stigmasterol

Steroids, 2012
Three new polyamine conjugates with stigmasterol [(3β,22E)-stigmasta-5,22-dien-3-ol] were synthesized and subjected to basic antimicrobial and cytotoxic tests. The conjugate derived from spermine, (3β,22E)-stigmasta-5,22-dien-3-yl 4(12-amino-4,9-diaza-dodecylamino)-4-oxobutanoate (5c), displayed considerable antimicrobial activity on Staphylococcus ...
Vida, Norbert   +6 more
openaire   +4 more sources

Stigmasterol Tetracosanoate, a New Stigmasterol Ester from the Egyptian Blepharis ciliaris

Drug Research, 2014
A new stigmasterol ester: stigmasterol tetracosanoate (3), along with 7 compounds: β-sitosterol (1), stigmasterol (2), (2S,3S,4R)-2[(2'R)-2'-(hydroxyeicosanoyl amino) octadecane-1,3,4-triol (4), apigenin (5), β-sitosterol-3-O-β-D-glucopyranoside (6), stigmasterol-3-O-β-D-glucopyranose (7), and apigenin-7-O-β-D-glucopyranoside (8) were isolated from ...
M A, El-Shanawany   +3 more
openaire   +2 more sources

Hydrogenation of stigmasterol

Lipids, 1973
AbstractHydrogenations of stigmasterol over 5% Pd/C, 5% Ru/C, Pt, Raney Ni, Raney Co, Ni/kieselguhr, and tris(triphenylphosphine)chlororhodium catalysts and with diimide generated from hydrazine andp‐toluenesulfonylhydrazide were studied to determine the best conditons for the selective reduction of the Δ22 double bond.
Henry W. Kircher, Fumiko U. Rosenstein
openaire   +1 more source

ChemInform Abstract: Stigmasterol Hemihydrate.

ChemInform, 2002
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Gloria A. Benavides   +2 more
openaire   +1 more source

Stigmasterol Removal by an Aerobic Treatment System

2023
Stigmasterol is a phytosterol contained in kraft mill effluent that is able to increase over 100% after aerobic biological treatment. This compound can act as an endocrine disrupter as its structure is similar to that of cholesterol. Furthermore, stigmasterol contained in kraft mill effluent shows high toxicity (25-fold more than β-sitosterol) to ...
Soledad, Chamorro   +2 more
openaire   +2 more sources

Biosynthesis of Stigmasterol in Tomato Fruits

Science, 1961
The presence of stigmasterol in tomato fruits was demonstrated. Labeled mevalonic acid was incorporated into this sterol, while sodium acetate was not. The identity of the isolated product was established by rigorous purification to constant specific activity, melting point determinations, and infrared ...
Bennett, Raymond D.   +3 more
openaire   +3 more sources

Stigmasterol protects rats from collagen induced arthritis by inhibiting proinflammatory cytokines.

International Immunopharmacology, 2020
Rheumatoid arthritis (RA) is an autoimmune disorder, in which imbalance in synthesis and production of inflammatory cytokines promotes cartilage and bone destruction.
Mahmood Ahmad Khan   +4 more
semanticscholar   +1 more source

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