Results 1 to 10 of about 53,540 (290)

Prognostic Perspectives of STING and PD-L1 Expression and Correlation with the Prognosis of Epstein-Barr Virus-Associated Gastric Cancers

Gut and Liver, 2022
Background/Aims: Epstein-Barr virus-associated gastric cancers (EBVaGCs) have unique molecular and clinicopathological characteristics. The cyclic GMP-AMP synthase-stimulator of interferon genes (STING) pathway is recently recognized as the critical ...
Qi Sun, Yao Fu, Xiaobing Chen, Lin Li, Hongyan Wu, Yixuan Liu, Haojun Xu, Guoren Zhou, Xiangshan Fan, Hongping Xia   +9 more
doaj   +1 more source

The Eurozone Crisis: A Constitutional Analysis

Utrecht Journal of International and European Law, 2015
“Every power comes through crisis” has long been a motif of European integration. The financial and sovereign debt crises, which have shaken the European Union (EU) in recent years, are at first glance no different. Treaty reforms,
Anna Sting
doaj   +3 more sources

The complete mitochondrial genome of a medical important wasp, Vespa magnifica (Hymenoptera, Vespidae)

Mitochondrial DNA. Part B. Resources, 2022
Vespa magnifica (Smith) is an aggressive social wasp species of Vespidae family. This species is of medical importance for its dangerous sting, traditional medicinal use and valuable venom components. Here, a complete mitogenome of V.
Xi Feng, Binqiang Xu, Yan Huang
doaj   +1 more source

The benefits of corporate social responsibility introduction in small and medium-sized enterprises: a systematic review of the literature

Business: Theory and Practice, 2016
Corporate social responsibility is considered as an important part of entrepreneur’s strategic behaviour. Its purpose is not only to achieve and maintain the good economic results, but at the same time also effort to do well to the environmental and ...
Monika Hodinková, Zdeněk Sadovský
doaj   +1 more source

DEVELOPMENTS WITHIN SOCIAL PEDAGOGY IN AUSTRIA: PERSPECTIVES FOR WORK WITH CHILDREN AND YOUNG PEOPLE

International Journal of Child, Youth & Family Studies, 2018
This article traces the history of social pedagogy in Austria, which shows some differences from the German history of social pedagogy. In the 1920s and the first half of the 1930s, the development of social pedagogy led to interesting approaches in the ...
Stephan Sting
doaj   +1 more source

Experimental Assays to Assess the Efficacy of Vinegar and Other Topical First-Aid Approaches on Cubozoan (Alatina alata) Tentacle Firing and Venom Toxicity

Toxins, 2016
Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that ...
Angel A. Yanagihara, Christie Wilcox, Rebecca King, Kikiana Hurwitz, Ann M. Castelfranco   +4 more
doaj   +1 more source

SV40 Large T Antigen Is Not Responsible for the Loss of STING in 293T Cells but Can Inhibit cGAS-STING Interferon Induction

Viruses, 2020
Several DNA viruses have evolved antagonists to inhibit the cyclic GMP−AMP synthase (cGAS)-stimulator of interferon genes (STING) DNA-sensing immune pathway.
Joshua B. Reus, Guillermo S. Trivino-Soto, Lily I. Wu, Kristiana Kokott, Efrem S. Lim   +4 more
doaj   +1 more source

STING-driven activation of T cells: relevance for the adoptive cell therapy of cancer

Cell Stress, 2023
Adoptive cell therapy (ACT) can successfully treat hema-topoietic cancers but lacks efficacy against solid tumors. This is due to insufficient T cell infiltration, high tumor heterogeneity, frequent antigen loss with subsequent tumor escape, and the ...
Fabian Richter, Christophe Paget, Lionel Apetoh   +2 more
doaj   +1 more source

Bioecology and chemical diversity of abdominal glands in the iranian samsum ant Pachycondyla sennaarensis (Formicidae: Ponerinae)

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
The genus Pachycondyla is a large group of ants in the Ponerini tribe, known mostly from tropical and subtropical regions. Pachycondyla sennaarensis, the so-called Samsum ant in the Middle East, is distributed throughout the African tropics, Arabian ...
MR Nikbakhtzadeh, K Akbarzadeh, S Tirgari   +2 more
doaj   +1 more source

The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression

OncoImmunology, 2017
Regressing tumors are usually associated with a large immune infiltrate, but the molecular and cellular interactions that govern a successful anti-tumor immunity remain elusive.
Julia M. Weiss, Marion V. Guérin, Fabienne Regnier, Gilles Renault, Isabelle Galy-Fauroux, Lene Vimeux, Vincent Feuillet, Elisa Peranzoni, Maxime Thoreau, Alain Trautmann, Nadège Bercovici   +10 more
doaj   +1 more source