Results 51 to 60 of about 30,783 (304)
Results in Physics, 2022 Statistical models perform an essential role in data analysis, and statisticians are constantly looking for novel or pretty recent statistical models to fit data sets across a broad variety of fields.
Anum Shafiq +2 more
doaj +1 more source
Stochastic frailty models for modeling and forecasting mortality
, 2021 In many countries life expectancy gains have been substantially higher than predicted by even recent forecasts. This is primarily due to increasing rates of improvement in old-age mortality not captured by existing models. In this paper we show how the concept of frailty can be used to model both changing rates of improvement and the deceleration of ...
openaire +2 more sources
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
A linear algebraic method for pricing temporary life annuities and insurance policies
, 2010 We recast the valuation of annuities and life insurance contracts under mortality and interest rates, both of which are stochastic, as a problem of solving a system of linear equations with random perturbations.
Mamon, R, Date, P, Wang, IC, Jalen, L
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Stochastic Models for the Consequences of Plasmodium Falciparum Infections in the Human Host: Malaria Morbidity, Mortality and Infectivity [PDF]
, 2008 The consequences of Plasmodium falciparum infections for humans range from selflimiting asymptomatic parasitaemia to rapid death. Annually, P. falciparum malaria is estimated to cause 0.5 billion acute febrile episodes, 2-3 million severe episodes ...
Ross, Amanda, Ross, Amanda
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Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
A stochastic implementation of the APCI model for mortality projections [PDF]
British Actuarial Journal, 2019 AbstractThe Age-Period-Cohort-Improvement (APCI) model is a new addition to the canon of mortality forecasting models. It was introduced by Continuous Mortality Investigation as a means of parameterising a deterministic targeting model for forecasting, but this paper shows how it can be implemented as a fully stochastic model.
S. J. Richards +3 more
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Pricing Survivor Bonds with Affine-Jump Diffusion Stochastic Mortality Models [PDF]
, 2021 Bravo, J. M. (2021). Pricing Survivor Bonds with Affine-Jump Diffusion Stochastic Mortality Models. In 2021 The 5th International Conference on E-Commerce, E-Business and E-Government ICEEG '21, April 28-30, 2021, Rome, Italy.
Jorge Miguel Bravo, Bravo, Jorge Miguel
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Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Contribution of early detection and adjuvant treatments to breast cancer mortality reduction in Catalonia, Spain. [PDF]
PLoS ONE, 2012 BACKGROUND: Reductions in breast cancer (BC) mortality in Western countries have been attributed to the use of screening mammography and adjuvant treatments.
Ester Vilaprinyo +2 more
doaj +1 more source