Results 141 to 150 of about 2,199 (176)

Retinol-guided liposomal platform for targeted pirfenidone delivery in hepatic fibrosis. [PDF]

open access: yesJ Nanobiotechnology
Chen J   +9 more
europepmc   +1 more source

Advances and therapeutic opportunities in visual cycle modulation. [PDF]

open access: yesProg Retin Eye Res
Zaluski J   +3 more
europepmc   +1 more source

STRA6 and Placental Retinoid Metabolism in Gestational Diabetes Mellitus [PDF]

open access: yesJournal of Personalized Medicine, 2021
Background: Recent reports indicate the potential role of the stimulated by retinoic acid 6 (STRA6) protein in developing insulin resistance. The study’s objective was to assess placental STRA6 expression and staining pattern in human pregnancy complicated by gestational diabetes mellitus (GDM). The expression pattern of further relevant genes involved
Ambrogio P Londero   +2 more
exaly   +8 more sources

O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes

open access: yesBiochimica Et Biophysica Acta - General Subjects, 2019
O-GlcNAcylation is an important mechanism of diabetic complication. Retinoid homeostasis regulates cell-physiological functions through STRA6-retinol signaling. Therefore, we investigated whether O-GlcNAcylation disrupted STRA6-retinol signals in diabetes.Immunoprecipitation and proximity ligation assay were used to investigate O-GlcNAcylation of STRA6-
Pi-Jung Hsiao   +2 more
exaly   +4 more sources

Structure of the STRA6 receptor for retinol uptake [PDF]

open access: yesScience, 2016
A window into the cell for vitamin A Vitamin A is an essential nutrient for mammals, and its metabolites affect diverse biological processes. It is carried in the bloodstream as retinol by retinol binding protein (RBP); a protein called STRA6 is implicated in facilitating retinol translocation across the cell membrane. Chen
Joachim Frank   +2 more
exaly   +3 more sources

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