Results 151 to 160 of about 2,199 (176)

STRA6 Promotes Thyroid Carcinoma Progression via Activation of the ILK/AKT/mTOR Axis in Cells and Female Nude Mice.

Endocrinology, 2023
Background: Metastasis has emerged to be an important cause for poor prognosis of thyroid carcinoma (TC) and its molecular mechanisms are not fully understood.
Shubin Hong, Haipeng Xiao, Yanbing Li
exaly   +2 more sources

Stra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage

Cell Death and Differentiation, 2013
Stra6 is the retinoic acid (RA)-inducible gene encoding the cellular receptor for holo-retinol binding protein. This transmembrane protein mediates the internalization of retinol, which then upregulates RA-responsive genes in target cells.
Salvador Macip i Maresma, Enrique Villar
exaly   +2 more sources

RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome [PDF]

Cell Metabolism, 2008
SummaryThe cellular uptake of vitamin A from its RBP4-bound circulating form (holo-RBP4) is a homeostatic process that evidently depends on the multidomain membrane protein STRA6.
Marcin Golczak, Krzysztof Palczewski, Johannes von Lintig   +2 more
exaly   +2 more sources

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Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor STRA6

Sub-Cellular Biochemistry, 2016
Vitamin A, retinol, circulates in blood bound to retinol binding protein (RBP). In some tissues, the retinol-RBP complex (holo-RBP) is recognized by a membrane receptor, termed STRA6, which mediates uptake of retinol into cells. Recent studies have revealed that, in addition to serving as a retinol transporter, STRA6 is a ligand-activated cell surface ...
Noa Noy
exaly   +3 more sources

Up-regulation of STRA6 predicts poor prognosis and contributes to oxaliplatin resistance in colorectal cancer

Pathology Research and Practice, 2023
Zhaohui Huang, Mingyang Li, Peiwen Xu
exaly  

Physiologically Relevant Free Ca Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6

Journal of Molecular Biology, 2021
Edwin Pozharski, Oliver B Clarke
exaly  

Calmodulin-STRA6 complex formation is regulated by Ca2+

Biophysical Journal, 2022
openaire   +1 more source

First implication of STRA6 mutations in isolated anophthalmia, microphthalmia, and coloboma: A new dimension to the STRA6 phenotype†

Human Mutation, 2011
Paul A McGettigan, Breandan N Kennedy, Derek W. Morris   +2 more
exaly  

miR-455-5p Overexpression Reduces Rat Lung Alveolar Type II Cell Proliferation by Downregulating STRA6

Anatomical Record, 2019
Huimin Xia, Qiuming He, Jintao Zheng
exaly  

Association analysis between STRA6 gene polymorphisms and carcass traits in Japanese black cattle.

Journal of Animal Genetics, 2020
Kei Hanzawa, Hiromi Hara
exaly