Results 71 to 80 of about 2,199 (176)
STRA6 (vitamin A receptor), as a Novel binding receptor of COVID-19 [PDF]
A global pandemic of pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Wuhan, China, at the end of 2019. Although, the ACE2 receptor has been shown to be the main entry receptor of COVID-19, but here, in our docking analysis , we predicted and discovered a novel receptor called STRA6 that may play a critical ...
Mahmoud Elkazzaz +3 more
openaire +1 more source
Obesity, characterized by augmented inflammation and tumorigenesis, is linked to genetic predispositions, such as FOXO3 polymorphisms. As obesity is associated with aberrant macrophages infiltrating different tissues, including the colon, we aimed to ...
Rida Iftikhar +7 more
doaj +1 more source
Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley +1 more source
Functional expression of STRA6-GFP in Pichia pastoris.
(A) Schematic of the STRA6-GFP-c-Myc-His6 construct designed in this study. The location of a HRV 3C protease cleavage site is indicated by the red cross.
Conor J. Breen (713888) +5 more
core +1 more source
This review illustrates the key mechanisms of osimertinib resistance in EGFR‑mutant NSCLC, including EGFR‑dependent mutations, bypass pathway activation, and SMARCA4‑mediated epigenetic regulation. We also summarize emerging targeted therapies and future perspectives to overcome EGFR‑TKI resistance.
Junfeng Guo, Qiuyuan Wen, Songqing Fan
wiley +1 more source
Background The ricefield eel is a protogynous hermaphroditic Synbranchiform species that changes sex naturally from female to male, which offers an interesting model for studying gonadal (particularly ovarian) differentiation in vertebrates.
Jinfeng Cai +6 more
doaj +1 more source
Vitamin A (VA) is essential for fetal lung development and postnatal lung maturation. VA is stored mainly as retinyl esters (REs), which may be mobilized for production of retinoic acid (RA).
Lili Wu, A. Catharine Ross
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Detergent screening of STRA6-GFP by FSEC.
The dispersity of STRA6-GFP was determined on a Superose 6, 10/300 GL column by FSEC in the following detergent complexes: (A) C12E9, (B) DM, (C) LDAO, (D) FC-12, (E) DDM, (F) DDM:CHS.
Conor J. Breen (713888) +5 more
core +1 more source
Genome-wide DNA methylation profiling in cultured eutopic and ectopic endometrial stromal cells. [PDF]
The objective of this study was to characterize the genome-wide DNA methylation profiles of isolated endometrial stromal cells obtained from eutopic endometria with (euESCa) and without endometriosis (euESCb) and ovarian endometrial cysts (choESC). Three
Yoshiaki Yamagata +6 more
doaj +1 more source

