Results 71 to 80 of about 1,534,439 (337)
The demand for military spending in Latin American countries
The allocation of resources to defence and national security is influenced by several factors, both domestic and external. Empirical findings suggest that military spending is determined by economic, strategic, political, and security factors.
Christos Kollias +3 more
doaj +1 more source
Strategic Planning at Five World-Class Companies [PDF]
Most successful executives know that strategic planning offers the best way to deal with their changing world. Information is central to successful strategic planning.
Akers, Michael D., Porter, Grover L
core +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Designing a Multi-Level Governance Model in Complex Organizations Based on Grounded Theory and Meta-Synthesis [PDF]
Objective: Multilevel governance is essential for achieving the vision and goals of today’s complex organizations. Therefore, the aim of this research is to present a multilevel governance model for complex organizations using a meta-synthesis of ...
Bahman Ebrahimian +4 more
doaj +1 more source
Information Provision for Strategic Planning in Bulgarian SMEs [PDF]
The information provision of strategic planning in small and medium sized enterprises (SMEs) is a subject that provokes the research interest due to the increased importance of strategic planning for the corporate development. This article - based on the
Emil PAPAZOV, Lyudmila MIHAYLOVA
core
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
DrugForm-DTA: Towards real-world drug-target binding affinity model
Drug-target affinity (DTA) prediction is a fundamental challenge in drug discovery. Computational methods for predicting DTA can greatly assist drug design by narrowing the search space and reducing the number of protein-ligand complexes with low ...
Ivan Khokhlov +8 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source

