Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management. [PDF]
Sakai T.
europepmc +1 more source
Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis +2 more
wiley +1 more source
LC-MS/MS Quantification and Comparative Profiling of Stratum Corneum Ceramides in Human Normal and Dry Skin Subtypes. [PDF]
Xie A +5 more
europepmc +1 more source
Post‐occlusion application of protective creams did not consistently reduce occlusion‐induced skin barrier impairment after glove use. Protective efficacy probably depends on formulation and timing, with only immediate pre‐irritant application showing a significant reduction in SLS‐induced barrier disruption.
Michal Gina +4 more
wiley +1 more source
Comparison of three multiplex immunoassays for biomarker analysis in stratum corneum tape strips. [PDF]
Metwally NKA +6 more
europepmc +1 more source
SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang +5 more
wiley +1 more source
Multiscale simulation of stratum corneum lipid mixtures: effects of ceramide headgroups on structural organization and hydrogen bonding networks. [PDF]
Frame CO +4 more
europepmc +1 more source
S1 Guideline: Therapy of generalized pustular psoriasis
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner +17 more
wiley +1 more source

