Results 151 to 160 of about 46,670 (310)

Understanding the effect of skin mechanical properties on the friction of human finger-pads [PDF]

, 2013
The aim of this work is to achieve an understanding of the effect of skin mechanical properties on the friction of human finger-pads. This project primarily concentrates on gaining a more fundamental understanding of the frictional properties of skin. To
Liu, Xiaoxiao
core  

Amphibian‐Derived Peptide OA‐AL14 Alleviates UVB‐Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway

Integrative Zoology, EarlyView.
The schematic diagram illustrates that the amphibian‐derived peptide OA‐AL14 protects against UVB‐induced skin photoaging through a dual mechanism: activating the Nrf2 pathway to counteract oxidative stress and modulating the AMPK/mTOR axis to induce protective autophagy. ABSTRACT Skin photoaging, primarily driven by ultraviolet B (UVB) radiation, is a
Ying Peng, Yutong Wu, Zhe Fu, Zijian Kang, Qiuye Jia, Wenbi Zhao, Ziyi Wang, Yuexi Liu, Ruijie Zhang, Yuansheng Li, Zeqiong Ru, Wenrou Su, Naixin Liu, Yilin Li, Saige Yin, Ying Wang, Xinwang Yang   +16 more
wiley   +1 more source

Active enhancement methods for intra- and transdermal drug delivery: a review

Zdravniški Vestnik, 2013
Transdermal route has some advantages over other drug administration routes. These include avoidance of first pass effect (hepatic metabolism), better pharmacokinetic profile, reduction of side effects and good patient compliance.
Barbara Zorec, Véronique Préat, Damijan Miklavčič, Nataša Pavšelj   +3 more
doaj  

Saving Water to Survive: Alternative Water Loss Strategies Could Explain Color Polymorphism Maintenance in a Lacertid Lizard

Integrative Zoology, EarlyView.
We demonstrate that red male Podarcis muralis exhibit higher evaporative water loss compared to other morphs, indicating a physiological strategy that prioritizes hydroregulation over fine thermoregulation. This suggests red morphs are adapted to cooler, wetter niches, while white and yellow morphs possess superior water conservation mechanisms to ...
Roberto Sacchi, Stefano Scali, Thomas Dadda, Federico Storniolo, Marco A. L. Zuffi, Andrea Melotto, Stéphanie Sherpa, Federica Frongia, Danny Tassi, Gentile Francesco Ficetola, Marco Mangiacotti   +10 more
wiley   +1 more source

Benzalkonium Chloride in Eye Drops Causing Allergic Contact Dermatitis: A Case Series

Australasian Journal of Dermatology, EarlyView.
ABSTRACT We present three patients who developed allergic contact dermatitis (ACD) from benzalkonium chloride (BAK) in ophthalmic drops. BAK is a preservative commonly found in ophthalmic formulations and there is a rising trend of ACD to this allergen. The irritant and sensitising properties of BAK on the ocular mucosa will be discussed.
Arav Kannen, Penelope Harrison, Elizabeth Christou   +2 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Distinct Skin Penetration and Immune Responses to Ionic and Nanoparticulate Cobalt in Allergic Contact Dermatitis

Allergy, EarlyView.
Cobalt chloride (CoCl2) and cobalt nanoparticles (CoNPs) induce a shared, severity‐dependent inflammatory response in cobalt‐sensitized skin characterized by activation of interferon signaling, inflammatory pathways (TNF/NF‐κβ, IL6‐STAT3), apoptosis/UPR, cell cycle programs, and glycolysis.
Paulina Werner, Martin Schaier, Gabriel Braun, Anneli Julander, Klara Midander, Marlene Isaksson, Gunda Koellensperger, Lukas Wisgrill, Nanna Fyhrquist   +8 more
wiley   +1 more source

Skin Abnormalities at Checkpoint Inhibitor Therapy Initiation Are Associated With Skin Rash Development in Oncology Patients

Allergy, EarlyView.
Skin tape strip lipidomic analysis revealed preexisting skin barrier lipid abnormalities at day 0 that were further exacerbated after 6 weeks of CPI treatment. Significant changes in skin (but not plasma) proinflammatory cytokines were identified in future ircAE patients after 6 weeks of CPI immunotherapy.
Taras Lyubchenko, Evgeny Berdyshev, Ryan M. Weight, Olivia Xiao, Neil J. Shah, Alina Markova, Mario E. Lacouture, Jeffrey A. Kern, Elena Goleva, Donald Y. M. Leung   +9 more
wiley   +1 more source

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

Allergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally, Takeshi Yoshida, Shan Gao, Xueya Cai, Donald Y. M. Leung, Lisa A. Beck, Anna De Benedetto   +6 more
wiley   +1 more source

Effects of a Moisturizer and Emollient on the Stratum Corneum Assessed by Confocal Raman Spectroscopy in Patients With and Without Atopic Dermatitis: An Assessor-Blinded Prospective Cohort Study. [PDF]

Health Sci Rep
Fukuda R, Hashimoto R, Pak K, Yasuda H, Mochimaru N, Matsumoto Y, Kiuchi M, Uematsu S, Yoshida K.   +8 more
europepmc   +1 more source