Results 131 to 140 of about 46,479 (310)

DEET‐cyclodextrin inclusion complexes for mosquito and tick repellency: Extended repellency time and no zebrafish embryotoxicity

Pest Management Science, EarlyView.
Hydroxypropyl‐β‐cyclodextrin (HPβCD)–N,N‐diethyl‐meta‐toluamide (DEET) complex extended tick repellency to 168 h. Full protection against Aedes aegypti for 7 h with HPβCD‐DEET. HPβCD reduced DEET release and skin retention significantly. No embryotoxicity observed below 325 mg L−1 in zebrafish model.
Gessyka Rayana Silva Pereira, Gleidson Cardoso, Maria Luiza Kuhn Camargo, Michele Resende Machado, Mayara Macedo Barrozo, Juscelino Rodrigues, Gisele Augusto Rodrigues de Oliveira, Caio Monteiro, Christian Luz, Ricardo Neves Marreto, Stephânia Fleury Taveira   +10 more
wiley   +1 more source

Ultrastructural Evidence of Stratum Corneum Permeabilization Induced by Photomechanical Waves

, 2003
Photomechanical waves (high amplitude pressure transients generated by lasers) have been shown to permeabilize the stratum corneum in vivo and facilitate the transport of macromolecules into the viable epidermis.
Menon, Gopinathan K., Doukas, Apostolos G., Kollias, Nikiforos   +2 more
core   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Imaging the electric field associated with mouse and human skin wounds

, 2008
We have developed a noninvasive instrument called the bioelectric field imager (BFI) for mapping the electric field between the epidermis and the stratum corneum near wounds in both mouse and human skin.
Sanger, Richard, Samdeo Ramlatchan, Richard Sanger, Nuccitelli, Richard, Peter J.S. Smith, Ramlatchan, Samdeo, Richard Nuccitelli, Nuccitelli, Pamela, Smith, Peter J.S., Pamela Nuccitelli   +9 more
core   +1 more source

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

Small, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu, Chunhao Long, Yuze Zhou, Lujing Fei, Youyou Zhou, Min Qi   +5 more
wiley   +1 more source

Ethnicity and stratum corneum ceramides

, 2010
BACKGROUND: The barrier function of the skin is dependent on an optimal composition of the stratum corneum lipids, exemplified by the altered lipid profile in patients with atopic eczema (AE).
J.M. Jungersted, Jungersted, J M, Høgh, J K, G.B.E. Jemec, L.I. Hellgren, Jemec, Gregor, Jemec, G., Agner, T, Jungersted, J.M., T. Agner, Agner, T., Høgh, Julie Kaae, J.K. Høgh, Hellgren, Lars   +13 more
core   +1 more source

Spatially Profiling Trace Cytokine Signatures From Microscopically Derived Skin Samples to Probe Skin Disease Inflammation

Small Methods, EarlyView.
Inflammatory skin diseases are driven by immune dysregulation and cytokine imbalance. A challenge persists in profiling cytokines in microscopically derived biopsy skin samples due to low protein content. This study introduces a digital SERS immunoassay to simultaneously detect IL‐17A, IL‐22, IL‐23, and TNF at trace concentrations as low as 104 aM. The
Aditya Krishnakumar, Zhen Zhang, Courtney Vedelago, Timothy J. Liu, Yung‐Ching Kao, H. Peter Soyer, Mitchell S. Stark, Snehlata Kumari, Matt Trau, Alain Wuethrich   +9 more
wiley   +1 more source

Preparation of Liposomes from Stratum Corneum Lipids

, 1986
Mammalian stratum corneum contains multiple intercellular lipid bilayers that contitute the epidermal water barrier. Unlike all other biologic membranes, the epidermal lamellae do not contain phospholipids, as a result of which the ability of the stratum
Downing, Donald T, Abraham, William, Wertz, Philip W, Landmann, Lukas   +3 more
core   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source