Contact and frictional properties of stratum corneum of human skin
Biosurface and Biotribology, 2015 Most skin tribology studies gave attention on the examination of frictional properties of normal and healthy skin surfaces. This study aims to investigate the frictional and mechanical properties of skin under different load and friction conditions after
Chien-Yu Chen +4 more
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Amino acids disrupt calcium-dependent adhesion of stratum corneum.
PLoS ONE, 2019 In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation in
Jin-Hyun Kim +7 more
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Investigating the Nanostructure of the Stratum Corneum Lipid Matrix: A Combined Neutron Diffraction & Molecular Dynamics Simulations Approach [PDF]
, 2022 The human skin provides a physiochemical and biological protective barrier to the body due to the unique structure of its outermost layer the stratum corneum. This layer consists of corneocytes and a multi-lamellar lipid matrix forming a composite, which
Rakesh, Gupta +4 more
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Measurement of drug diffusivity in stratum corneum membranes and a polyacrylate matrix [PDF]
, 1991 Diffusivities have been determined for the drug clenbuterol for three non-sink, diffusional problems: diffusion out of a polymer matrix, diffusion through excised, human stratum corneum, and the combined case of diffusion out of a polymer matrix through ...
Lee, Geoffrey, Göpferich, Achim
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The pH of the skin surface and its impact on the barrier function [PDF]
, 2006 The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Korting, Hans Christian +1 more
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Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]
, 2008 In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
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Evaluation of topical bioavailability in human stratum corneum in vivo by tape stripping using a direct sprectroscopic method [PDF]
, 2006 The objective of this thesis was to develop a spectrophotometric methodology for simultaneous determination of a sunscreening agent and relative stratum corneum tissue density in skin tape strips.
Fässler Tassopoulos, Tatiana
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Surfactants and the stratum corneum lipids [PDF]
, 1987 A simplified mixture of model stratum corneum lipids was mixed with different surfactants to make a preliminary estimation of the influence of surfactants on the stratum corneum lipid structure.
Stig E. Friberg +7 more
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Two-Photon Fluorescence Lifetime Imaging of the Skin Stratum Corneum pH Gradient [PDF]
, 2002 Two-photon fluorescence lifetime imaging is used to identify microdomains (1–25μm) of two distinct pH values within the uppermost layer of the epidermis (stratum corneum).
Gratton, E +11 more
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Elucidating the molecular landscape of the stratum corneum
, 2022 • Characterization of the molecular structure of skin, especially the barrier layer, the stratum corneum using 3D OrbiSIMS. • Understand the chemical variations relating to fundamental biological processes, such as the epidermal cholesterol sulfate ...
Alexander, Morgan R. +11 more
core +1 more source