Results 11 to 20 of about 46,479 (310)

The Fibrous Proteins Of Stratum Corneum

open access: yesJournal of Investigative Dermatology, 1976
The proteins of cow snout stratum corneum can be extracted in part with Tris buffer, pH 9.0, containing 6 M urea. Sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis shows that about half the extracted material migrates as prekeratin when the extract is treated with both SDS and mercaptoethanol; only trace amounts of the proteins migrating ...
Baden, H.P., Lee, L.D., Kubilus, J.
openaire   +3 more sources

The pH of the skin surface and its impact on the barrier function [PDF]

open access: yes, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Korting, Hans Christian   +1 more
core   +1 more source

Effect of continuous phase drug concentration, evaporation and partitioning on transdermal drug permeation kinetics with lipophilic vehicles [PDF]

open access: yes, 2008
In this work the dependence of transdermal drug permeation kinetics on continuous phase drug concentration, partitioning between formulation phases, partitioning between stratum corneum and continuous oil phase and evaporation of volatile formulation ...
Reiser, Miriam Regina Luise
core   +1 more source

Evaluation of topical bioavailability in human stratum corneum in vivo by tape stripping using a direct sprectroscopic method [PDF]

open access: yes, 2006
The objective of this thesis was to develop a spectrophotometric methodology for simultaneous determination of a sunscreening agent and relative stratum corneum tissue density in skin tape strips.
Fässler Tassopoulos, Tatiana
core   +1 more source

Electrochemical microsensors for cutaneous surface analysis: Application to the determination of pH and the antioxidant properties of stratum corneum [PDF]

open access: yes, 2008
Potentiometry and cyclic voltammetry were proposed as simple, reliable and non invasive methods for the simultaneous determination of pH and antioxidant properties of skin.
Ruffien-Ciszak, A   +9 more
core   +1 more source

Topical bioavailability of glucocorticosteroids : dermatopharmacokinetic and dermatopharmacodynamic of topically applied triamcinolone acetonide in humans [PDF]

open access: yes, 2006
The aim of the present thesis was the in vivo investigation of the topical bioavailability of a model glucocorticosteroid, triamcinolone acetonide (TACA), using tape stripping. The layer by layer removal of the stratum corneum by tape stripping enables
Pellanda, Carolina
core   +1 more source

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

open access: yesJournal of Lipid Research, 2012
The acyl-CoA binding protein (ACBP) is a 10 kDa intracellular protein expressed in all eukaryotic species. Mice with targeted disruption of Acbp (ACBP−/− mice) are viable and fertile but present a visible skin and fur phenotype characterized by greasy ...
Maria Bloksgaard   +18 more
doaj   +1 more source

Impact of Age and Body Site on Adult Female Skin Surface pH [PDF]

open access: yes, 2012
Background: pH is known as an important parameter in epidermal barrier function and homeostasis. Aim: The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
Korting, Hans Christian   +7 more
core   +1 more source

10-Hydroxy-2-Decenoic Acid in Royal Jelly Extract Induced Both Filaggrin and Amino Acid in a Cultured Human Three-Dimensional Epidermis Model

open access: yesCosmetics, 2017
Royal jelly (RJ) is a natural product which the honeybee secretes as a special diet for a queen bee. It is one of the natural products in which various functionalities, such as antibacterial effects, immunomodulating properties, and estrogen-like action,
Lihao Gu, Haifeng Zeng, Kazuhisa Maeda
doaj   +1 more source

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.

open access: yesJournal of Lipid Research, 1995
The intercellular lipid regions in the stratum corneum (SC), the outermost layer of the skin, form the major barrier for diffusion of substances through the skin. The barrier function of in vitro reconstructed epidermis is still impaired. With respect to
J A Bouwstra   +4 more
doaj   +1 more source

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