Results 21 to 30 of about 139,184 (387)
Data in Brief, 2017 The data in this article shows the effect of isopropyl myristate (IPM) on a 2D Stratum Corneum lipid model. In the first part, the analytical characterization of the synthesized deuterated isopropyl myristate is given.
J.S.L. Oliveira +3 more
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Predicting Skin Permeability by means of Computational Approaches : Reliability and Caveats in Pharmaceutical Studies [PDF]
, 2019 © 2019 American Chemical Society.The skin is the main barrier between the internal body environment and the external one. The characteristics of this barrier and its properties are able to modify and affect drug delivery and chemical toxicity parameters.
Almerico, Anna Maria +5 more
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Human epidermal lipids: characterization and modulations during differentiation
Journal of Lipid Research, 1983 Using thin-layer chromatography and glass capillary gas-liquid chromatography, we have quantitated the lipids in the germinative, differentiating, and fully cornified layers in human epidermis.
M A Lampe, M L Williams, P M Elias
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Chemical Enhancer: A Simplistic Way to Modulate Barrier Function of the Stratum Corneum
Advanced Pharmaceutical Bulletin, 2018 Human skin could be a prime target to deliver drugs into the human body as it is the largest organ of human body. However, the main challenge of delivering drug into the skin is the stratum corneum (SC), the outer layer of epidermis, which performs the ...
T. Haque, M. Talukder
semanticscholar +1 more source
Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis
Journal of Lipid Research, 2003 To clarify the functional relevance of sphingomyelin (100) deacylase to the ceramide deficiency seen in atopic dermatitis (AD), we developed a new highly sensitive method and measured the metabolic intermediate sphingosylphosphorylcholine (SPC) that ...
Reiko Okamoto +5 more
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Non-invasive depth profiling of the stratum corneum in vivo using confocal Raman microscopy considering the non-homogeneous distribution of keratin [PDF]
, 2019 Confocal Raman microscopy has a number of advantages in investigating the human stratum corneum (SC) in vivo and ex vivo. The penetration profiles of xenobiotics in the SC, as well as depth profiles of the physiological parameters of the SC, such as the ...
Choe, Chun-Sik +3 more
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Review of Stratum Corneum Impedance Measurement in Non-Invasive Penetration Application
Biosensors, 2018 Due to advances in telemedicine, mobile medical care, wearable health monitoring, and electronic skin, great efforts have been directed to non-invasive monitoring and treatment of disease.
F. Lu +6 more
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The physics of stratum corneum lipid membranes [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2015 The stratum corneum (SC), the outermost layer of skin, comprises rigid corneocytes (keratin-filled dead cells) in a specialized lipid matrix. The continuous lipid matrix provides the main barrier against uncontrolled water loss and invasion of external ...
Chinmay Das, P. Olmsted
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Journal of Lipid Research, 2018 Neu-Laxova syndrome (NLS) is a very rare autosomal recessive congenital disorder characterized by disturbed development of the central nervous system and the skin and caused by mutations in any of the three genes involved in de novo l-serine biosynthesis:
Takuya Takeichi +14 more
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Molecules, 2018 The skin permeability (Kp) defines the rate of a chemical penetrating across the stratum corneum. This value is widely used to quantitatively describe the transport of molecules in the outermost layer of epidermal skin and indicate the significance of ...
Chen-Peng Chen +3 more
semanticscholar +1 more source