Results 21 to 30 of about 66,927 (286)

Water permeation through stratum corneum lipid bilayers from atomistic simulations [PDF]

, 2009
Stratum corneum, the outermost layer of skin, consists of keratin filled rigid non-viable corneocyte cells surrounded by multilayers of lipids. The lipid layer is responsible for the barrier properties of the skin.
Bemporad, Berendsen, Berger, Blank, Bondi, Bouwstra, Chinmay Das, Chiu, Das, den Otter, Falck, Farwanah, Golden, Hara, Hoover, Hänggi, Höltje, Jacobson, Jorgensen, Kasting, Lodén, Mark, Marrink, Massimo G. Noro, Michaels, Miyamoto, Norlén, Norlén, Nosé, Nosé, Notman, Parrinello, Peter D. Olmsted, Pieper, Potts, Prausnitz, Ryckaert, Ryckaert, Schatzberg, Scheuplein, Schätzlein, Sugii, van der Spoel, Weerheim   +43 more
core   +2 more sources

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

Journal of Lipid Research, 2012
The acyl-CoA binding protein (ACBP) is a 10 kDa intracellular protein expressed in all eukaryotic species. Mice with targeted disruption of Acbp (ACBP−/− mice) are viable and fertile but present a visible skin and fur phenotype characterized by greasy ...
Maria Bloksgaard, Signe Bek, Ann-Britt Marcher, Ditte Neess, Jonathan Brewer, Hans Kristian Hannibal-Bach, Torben Helledie, Christina Fenger, Marianne Due, Zane Berzina, Reinhard Neubert, John Chemnitz, Bente Finsen, Anders Clemmensen, Johannes Wilbertz, Henrik Saxtorph, Jens Knudsen, Luis Bagatolli, Susanne Mandrup   +18 more
doaj   +1 more source

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.

Journal of Lipid Research, 1995
The intercellular lipid regions in the stratum corneum (SC), the outermost layer of the skin, form the major barrier for diffusion of substances through the skin. The barrier function of in vitro reconstructed epidermis is still impaired. With respect to
J A Bouwstra, G S Gooris, A Weerheim, J Kempenaar, M Ponec   +4 more
doaj   +1 more source

Topical Application of Metal Allergens Induces Changes to Lipid Composition of Human Skin

Frontiers in Toxicology, 2022
Lipids are an important constituent of skin and are known to be modified in many skin diseases including psoriasis and atopic dermatitis. The direct effects of common metallic contact allergens on the lipid composition of skin has never been investigated,
Sophie Knox, Lina Hagvall, Per Malmberg, Niamh M. O'Boyle   +3 more
doaj   +1 more source

Electrochemical microsensors for cutaneous surface analysis: Application to the determination of pH and the antioxidant properties of stratum corneum [PDF]

, 2008
Potentiometry and cyclic voltammetry were proposed as simple, reliable and non invasive methods for the simultaneous determination of pH and antioxidant properties of skin.
Baur, Jessica, Comtat, Maurice, Gros, Pierre, Questel, Emmanuel, Ruffien-Ciszak, Audrey   +4 more
core   +2 more sources

Stratum corneum dysfunction in dandruff [PDF]

International Journal of Cosmetic Science, 2012
SynopsisDandruff is characterized by a flaky, pruritic scalp and affects up to half the world’s population post‐puberty. The aetiology of dandruff is multifactorial, influenced by Malassezia, sebum production and individual susceptibility. The commensal yeast Malassezia is a strong contributory factor to dandruff formation, but the presence of ...
Turner, G A, Hoptroff, M, Harding, C R
openaire   +2 more sources

By protecting against cutaneous inflammation, epidermal pigmentation provided an additional advantage for ancestral humans. [PDF]

, 2019
Pigmentation evolved in ancestral humans to protect against toxic, ultraviolet B irradiation, but the question remains: "what is being protected?" Because humans with dark pigmentation display a suite of superior epidermal functions in comparison with ...
Abuabara, Katrina, Elias, Peter M, Lee, Chih-Hung, Lin, Tzu-Kai, Man, Mao-Qiang, Sheu, Hamm-Ming, Tsai, Jui-Chen, Wakefield, Joan S   +7 more
core   +1 more source

RELATIONSHIP BETWEEN STRATUM CORNEUM OF DUCTUS PAPILLARIS AND UDDER PARENCHYMA IN COWS

Archives of Veterinary Medicine, 2011
From 26 cows of Holstein-Friesian, which had been excluded from production for diff erent etiologic reasons, the udder was taken in order to monitor the changes that appeared in cow’s udder parenchyma. Aft er macroscopic examination, the tops of papillae
Ivana Davidov, Miodrag Radinović, Dragica Stojanović   +2 more
doaj   +1 more source

Mathematical Modelling of Chemical Diffusion through Skin using Grid-based PSEs [PDF]

, 2008
A Problem Solving Environment (PSE) with connections to remote distributed Grid processes is developed. The Grid simulation is itself a parallel process and allows steering of individual or multiple runs of the core computation of chemical diffusion ...
C Upson, CE Goodyer, EL Cussler, HF Frasch, I Foster, M Heisig, MA Walkley, ME Johnson, SG Parker   +8 more
core   +1 more source

Recent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin

Cosmetics, 2019
Human skin is the largest organ of the body and is an effective physical barrier keeping it from environmental conditions. This barrier function of the skin is based on stratum corneum, located in the uppermost skin.
Emine Kahraman, Melis Kaykın, Hümeyra Şahin Bektay, Sevgi Güngör   +3 more
doaj   +1 more source