Results 211 to 220 of about 318,069 (262)

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Mechanozyme: An Artificial Enzyme With a Mechanophore Framework

Advanced Science, EarlyView.
Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji, Pravin Pokhrel, Sajan Shakya, Bishal Pokhrel, Grinsun Sharma, Pratiksha Chaudhary, Hao Shen, Hanbin Mao   +7 more
wiley   +1 more source

Automated Generation of Supported Lipid Bilayer Arrays with Controlled Receptor Densities in Well Plates. [PDF]

ACS Appl Mater Interfaces
Schlicke J, Movilli J, Wasserberg D, Biendara RN, Aphrham S, Jonkheijm P, Uslu E, Boons GPH, Molenaar R, Elbert R, de Wit S, van der Vries E, Huskens J.   +12 more
europepmc   +1 more source

Breaking the Bottleneck in Limit of Detection of Surface Refractive Index Sensing by Harnessing Meta‐Waveguide Microring Resonators

Advanced Science, EarlyView.
Mode splitting in meta‐waveguide microring resonators (MWMRs) effectively suppresses baseline drift and measurement noise while maintaining high refractive‐index sensitivity. This reflection‐induced mode splitting strategy enables quantitative detection of ultra‐weak surface perturbations and establishes MWMRs as a robust, drift‐immune platform for ...
Wanxin Li, Jiewen Li, Rui Li, Gina Jinna Chen, Perry Ping Shum, Yi Zou, Ray T. Chen, Yongkang Dong, Xiaochuan Xu   +8 more
wiley   +1 more source

Association between anti-nephrin autoantibodies and disease activity in minimal change disease. [PDF]

Ann Med
Guo M, Yan L, Zhao J, Liu X, Zhang H, Li M, Zhang K, Cui J, Wang Y, Chen X, Dong Z, Li Q.   +11 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

Advanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li, Xin Xing, Beicheng Du, Myles Zhou, Austin Z. Chen, Mary Archer, Chunbao Rao, Manyu Zhu, Masnsen Cherief, Aaron W. James   +9 more
wiley   +1 more source

Proximity labelling identifies proteins associated with HSV-2 pUL21 at early and late times after infection. [PDF]

PLoS Pathog
Holder SM, Bossert M, Finnen RL, Banfield BW.   +3 more
europepmc   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci. [PDF]

Elife
Liu Y, McGann CD, Herlihy CP, Krebs M, Perkins TA, Fields R, Camplisson CK, Nwizugbo DZ, Lin Q, Longhi NJ, Hsu C, Avanessian SC, Tsue AF, Kania EE, Shechner DM, Beliveau BJ, Schweppe DK.   +16 more
europepmc   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun, Jing Zhang, Chenqing Liu, Jing Lou, Sihui Wang, Xiangtian Ji, Xiaofang Zhao, Shirui Xu, Jingyu Feng, Bin Liu, Chao Chang, Qinggang Ge, Jun Yang   +12 more
wiley   +1 more source