Results 231 to 240 of about 318,069 (262)

MAPK Pathway Inhibition Reshapes Kinase Chemical Probe Reactivity Reflecting Cellular Activation States. [PDF]

ACS Bio Med Chem Au
Jarvis AF, Bhat MY, Maujean T, Abreu AL, Toy K, Burslem GM, Brady DC.   +6 more
europepmc   +1 more source

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

Annals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu, Youqi Tao, Alexandra M. Lish, Shaomin Li, Beth L. Ostaszewski, Amirah K. Anderson, Tracy Young‐Pearse, Trebor L. Lawton, Hyun‐Sik Yang, Dominic M. Walsh, Ting Yang, Dennis J. Selkoe   +11 more
wiley   +1 more source

Improved T Cell Surfaceomics by Depleting Intracellularly Labelled Dead Cells. [PDF]

Mol Cell Proteomics
Sánchez CD, Balakrishnan A, Krisko B, Ahmmed B, Witchey L, Valenzuela O, Minasyan M, Pak A, Mkhikian H.   +8 more
europepmc   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

Annals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones, Blessing Nyakutsikwa, Michael H. Askenase, Matthew Gittins, Mary Newland, Siobhan Crilly, Paul R. Kasher, Yvonne Davidson, Federico Roncaroli, Stuart M. Allan, Lauren H. Sansing, Wendy Ziai, Daniel F. Hanley, INFLAME‐ICH Investigators, Mark Harrigan, David Miller, Judy Huang, Wendy Ziai, Jack Jallo, Fred Rincon, Gaurav Gupta, Igor Rybinnik, Diederik Bulters, Mary Leigh Gelea, Andras Buki, Erzsebet Ezer, Hiren Patel, Adrian Parry‐Jones, Charles Matouk, Kevin Sheth / Lauren Sansing, Ali Zomorodi, Michael James, Pal Barzo, Krisztian Tanczos, Gregory Thompson, Ventatakrishna Rajajee/Aditya Pandey, Peter Nakaji, Shawn E. Wright, Walter Galicich, Thomas Bergman, Andrew Carlson, Huy Tran, Philipp Taussky, Safdar Ansari, Fuat Arikan, Marcelino Baguena, Ronald Reimer, W. David Freeman, Ania Pollack, John Terry, Geza Mezey, Katalin Szabo/Laszlo Csiba, Robert F. James, Steven J. Barrer, Larami MacKenzie   +54 more
wiley   +1 more source

Consecutive Mechano-Immunophenotyping of Single Cells in a Photopatterned Microfluidic Channel. [PDF]

ACS Omega
Nomiyama T, Ide S, Kaji N.
europepmc   +1 more source

Monitoring Endocytosis of Integral Membrane Proteins Using Western Blot-Based Detection of Biotinylated Antibody Uptake. [PDF]

Bio Protoc
Graninger A, Satpute-Krishnan P.
europepmc   +1 more source

Oculopharyngeal muscular dystrophy (OPMD) associated alanine expansion impairs the function of the nuclear polyadenosine RNA binding protein PABPN1 as revealed by proximity labeling and comparative proteomics. [PDF]

PLoS Genet
Mezzell AT, Zhang Y, Perez AM, Vest KE.
europepmc   +1 more source

Nanopore Trap for Label-Free Fingerprinting of Surface-modified Single Nanoparticles. [PDF]

Small Methods
Cai N, Chen TH, Teng Y, Naidu AS, Radenovic A.   +4 more
europepmc   +1 more source

Protein chirality as a determinant of ligand affinity: insights from l- and d-streptavidin. [PDF]

Chem Sci
Giesler RJ, Woodham PCS, Draper SRE, Spaltenstein P, Whitby FG, Hill CP, Kay MS.   +6 more
europepmc   +1 more source