Results 221 to 230 of about 326,708 (370)

Intravesical Tumor-Selective Mucoadhesive Hydrogel for Effective Chemotherapy In Murine Model. [PDF]

Int J Nanomedicine
Zheng B, Chen Z, Sun L, Quan J, Wei J, Huang B, Zhang D, Zhang P, Zhuo Y.   +8 more
europepmc   +1 more source

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science, EarlyView.
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
wiley   +1 more source

Assembly of a gene sequence tag microarray by reversible biotin-streptavidin capture for transcript analysis of Arabidopsis thaliana. [PDF]

, 2005
Valtteri Wirta, Anders Holmberg, Morten Lukacs, Peter Nilsson, Pierre Hilson, Mathias Uhlén, Rishikesh P. Bhalerao, Joakim Lundeberg   +7 more
openalex   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Development of a Homogeneous Time-Resolved Fluorescence Assay for High Throughput Screening to Identify Lck Inhibitors: Comparison with Scintillation Proximity Assay and Streptavidin-Coated Plate Assay

, 2000
Natsue Ohmi, Jonathan Wingfield, Hidenori Yazawa, Osamu Inagaki   +3 more
openalex   +1 more source

Streptavidin surprises [PDF]

, 2005
Allison Doerr
openalex   +1 more source

Accessibility of Targeted DHPR Sites to Streptavidin and Functional Effects of Binding on EC Coupling [PDF]

, 2007
Nancy M. Lorenzon, Kurt G. Beam
openalex   +2 more sources

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

Cooperative hydrogen bond interactions in the streptavidin–biotin system [PDF]

, 2006
David E. Hyre, Isolde Le Trong, E.A. Merritt, John F. Eccleston, N. Michael Green, Ronald E. Stenkamp, Patrick S. Stayton   +6 more
openalex   +1 more source

TurboID Labeling and Analysis of Proteins in the Primary Cilium. [PDF]

Bio Protoc
Liu X, Ge X.
europepmc   +1 more source