Results 251 to 260 of about 326,708 (370)
Streptavidin Binding and Endothelial Cell Adhesion to Biotinylated Fibronectin [PDF]
, 2007 Charles C. Anamelechi +4 more
openalex +1 more source
Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology
Angewandte Chemie, EarlyView.Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects.
Andrew G. Baker +3 more
wiley +2 more sources
Improvement of the optical cavity-based biosensor's limit of detection using optimal 3-aminopropyltriethoxysilane process. [PDF]
Sci RepSypabekova M +6 more
europepmc +1 more source
Animal Models and Experimental Medicine, EarlyView.The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou +5 more
wiley +1 more source
Functional Ambidexterity of an Ancient Nucleic Acid‐Binding Domain
Angewandte Chemie, EarlyView.The (HhH)2‐Fold is an ancient and ubiquitous nucleic acid‐binding domain. We demonstrate that this domain, which interacts with the minor groove of dsDNA, is functionally ambidextrous – that it can bind to dsDNA of either chirality. Moreover, binding of both chiral forms of dsDNA is mediated by an overlapping binding surface.
Orit Weil‐Ktorza +8 more
wiley +2 more sources
Unraveling Charge Transfer Mechanisms in Graphene-Quantum Dot Hybrids for High-Sensitivity Biosensing. [PDF]
Biosensors (Basel)Francis SM, Sanabria H, Podila R.
europepmc +1 more source
Comparison of the pathogenicity of multiple SARS‐CoV‐2 variants in mouse models
Animal Models and Experimental Medicine, EarlyView.We assessed the pathogenicity of various SARS‐CoV‐2 variants using two distinct mouse models. Our findings indicated that earlier variants, including WH‐09, Beta, and Delta, exhibited greater pathogenicity than later variants. Specifically, the Omicron variant demonstrated reduced pathogenicity, characterized by a shorter disease course and diminished ...
Qi Lv +12 more
wiley +1 more source
Magnetically Localized Detection of Amplified DNA Using Biotinylated and Fluorescent Primers and Magnetic Nanoparticles. [PDF]
Biosensors (Basel)Orsini E +5 more
europepmc +1 more source
Angewandte Chemie, EarlyView.Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yue Yuan +6 more
wiley +2 more sources