Results 1 to 10 of about 26,114 (192)

Streptokinase and Myocardial Infarction [PDF]

open access: greenNew England Journal of Medicine, 1979
The results of several multicenter studies on the treatment of acute myocardial infarction with streptokinase are now in. Although the results are variable and, when all of the trials are considered, the impact on overall mortality is rather small, the report appearing in today's Journal suggests that a subgroup of "medium-risk" patients benefit from ...
Jay M. Sullivan
openaire   +5 more sources

Interaction of Streptokinase and Plasminogen [PDF]

open access: yesJournal of Biological Chemistry, 1995
The interaction of streptokinase (SK) with human plasminogen (HPlg) was investigated using truncated SK peptides prepared by gene cloning techniques. SK(16-414) and SK(16-378) could activate HPlg as efficiently as the authentic SK. SK(60-414), which had been preincubated with SK(1-59), could also activate HPlg. SK(91-414), SK(127-414), and SK(158-414),
Hua Lin Wu   +7 more
openaire   +3 more sources

Preintensive care: Thrombolytic (streptokinase or tenecteplase) in ST elevated acute myocardial infarction at peripheral hospital

open access: yesJournal of Family Medicine and Primary Care, 2019
Background: Coronary artery disease is a major cause of death in India. Sudden death preceded by chest pain is due to acute myocardial infarction. Villagers are aware and afraid of chest pain.
H. Bawaskar, P. Bawaskar, P. Bawaskar
semanticscholar   +1 more source

Antibodies to streptokinase [PDF]

open access: yesBMJ, 1996
Once is enough Thrombolysis is established treatment in the early management of myocardial infarction, and it reduces 35 day mortality by about a quarter.1 The GUSTO study has suggested some advantage of alteplase (rt-PA) over streptokinase with regard to early patency of the occluded coronary artery.2 In particular, GUSTO has suggested that patients ...
openaire   +3 more sources

Streptokinase and facial haematoma [PDF]

open access: yesPostgraduate Medical Journal, 1995
Abstract We report two cases of facial haematoma following streptokinase therapy. This is an important complication as it can have fatal consequences. Early recognition and close monitoring are essential as emergency intervention may be required.
J. D. T. Mason, P. Jervis, N. S. Jones
openaire   +3 more sources

Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes

open access: yesPLoS ONE, 2017
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish, C. Thelwell, C. Longstaff
semanticscholar   +1 more source

Streptococcus pyogenes Escapes Killing from Extracellular Histones through Plasminogen Binding and Activation by Streptokinase

open access: yesJournal of Innate Immunity, 2016
Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins.
R. Nitzsche   +3 more
semanticscholar   +1 more source

Optimization of culture media for extracellular expression of streptokinase in Escherichia coli using response surface methodology in combination with Plackett-Burman Design

open access: yes, 2018
Purpose: To investigate the enhancement of streptokinase extracellular expression in Escherichia coli by adjusting culture media. Methods: Screening of 10 chemical factors (EDTA, peptone, glycine, triton X-100, glycerol, K 2 HPO 4 , KH 2 PO 4 , Ca 2 ...
Mojtaba Aghaeepoor   +6 more
semanticscholar   +1 more source

Analysis of Outcome of Intraplueral Streptokinase in Pediatric Empyema Thoracis even in Advanced Stages: A Prospective Study

open access: yesIranian Journal of Pediatrics, 2015
Background: Empyema thoracis in children causes significant morbidity. Standard treatment of Empyema thoracis includes tube drainage and antibiotics. But the tube drainage often fails.
K. Bose   +5 more
semanticscholar   +1 more source

Streptokinase resistance: when might streptokinase administration be ineffective? [PDF]

open access: yesHeart, 1992
(a) To develop an assay for streptokinase resistance. (b) To determine the prevalence of streptokinase resistance in patients presenting with acute myocardial infarction for the first time. (c) To determine the prevalence of streptokinase resistance in patients after exposure to streptokinase or streptococcal infection.Open, prospective.30 healthy ...
Trevor Baglin   +8 more
openaire   +3 more sources

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