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Streptokinase and Myocardial Infarction [PDF]
The results of several multicenter studies on the treatment of acute myocardial infarction with streptokinase are now in. Although the results are variable and, when all of the trials are considered, the impact on overall mortality is rather small, the report appearing in today's Journal suggests that a subgroup of "medium-risk" patients benefit from ...
Jay M. Sullivan
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Interaction of Streptokinase and Plasminogen [PDF]
The interaction of streptokinase (SK) with human plasminogen (HPlg) was investigated using truncated SK peptides prepared by gene cloning techniques. SK(16-414) and SK(16-378) could activate HPlg as efficiently as the authentic SK. SK(60-414), which had been preincubated with SK(1-59), could also activate HPlg. SK(91-414), SK(127-414), and SK(158-414),
Hua Lin Wu+7 more
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Background: Coronary artery disease is a major cause of death in India. Sudden death preceded by chest pain is due to acute myocardial infarction. Villagers are aware and afraid of chest pain.
H. Bawaskar, P. Bawaskar, P. Bawaskar
semanticscholar +1 more source
Antibodies to streptokinase [PDF]
Once is enough Thrombolysis is established treatment in the early management of myocardial infarction, and it reduces 35 day mortality by about a quarter.1 The GUSTO study has suggested some advantage of alteplase (rt-PA) over streptokinase with regard to early patency of the occluded coronary artery.2 In particular, GUSTO has suggested that patients ...
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Streptokinase and facial haematoma [PDF]
Abstract We report two cases of facial haematoma following streptokinase therapy. This is an important complication as it can have fatal consequences. Early recognition and close monitoring are essential as emergency intervention may be required.
J. D. T. Mason, P. Jervis, N. S. Jones
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Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis.
Sian Huish, C. Thelwell, C. Longstaff
semanticscholar +1 more source
Histones are small basic proteins and highly conserved among eukaryotes. Their main function is binding, packaging and organizing of DNA in the nucleus, but extracellular histones are also potent antimicrobial proteins.
R. Nitzsche+3 more
semanticscholar +1 more source
Purpose: To investigate the enhancement of streptokinase extracellular expression in Escherichia coli by adjusting culture media. Methods: Screening of 10 chemical factors (EDTA, peptone, glycine, triton X-100, glycerol, K 2 HPO 4 , KH 2 PO 4 , Ca 2 ...
Mojtaba Aghaeepoor+6 more
semanticscholar +1 more source
Background: Empyema thoracis in children causes significant morbidity. Standard treatment of Empyema thoracis includes tube drainage and antibiotics. But the tube drainage often fails.
K. Bose+5 more
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Streptokinase resistance: when might streptokinase administration be ineffective? [PDF]
(a) To develop an assay for streptokinase resistance. (b) To determine the prevalence of streptokinase resistance in patients presenting with acute myocardial infarction for the first time. (c) To determine the prevalence of streptokinase resistance in patients after exposure to streptokinase or streptococcal infection.Open, prospective.30 healthy ...
Trevor Baglin+8 more
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