Results 1 to 10 of about 9,508 (146)

Emphasizing the Pharmacological Potentials of the Methanolic Extract of Wedelia montana: A Prominent Source of Veterinary Medicine. [PDF]

Vet Med Int
The research focused on Wedelia montana (Blume) Boerl because of its numerous medicinal applications. W. montana belongs to the Asteraceae family. This investigation is intended to analyze the phytochemical content of the methanol extract of W. montana (MEWM) and evaluate its biological features by utilizing in vitro and in vivo models.
Mesu MH, Uddin Chowdhury MA, Arman M, Jahan I, Shill SK, Mamun MA, Islam Mamun MJ, Alim MA, Chowdhury MT, Hossen SMM.   +9 more
europepmc   +2 more sources

Multimodal Pharmacological Assessment of <i>Arenga porphyrocarpa</i> Palm Leaves and Stems Extracts: Insights From In Vivo, In Vitro, and In Silico Approaches. [PDF]

Food Sci Nutr
Arenga porphyrocarpa leaf and stem extracts demonstrated significant neuropharmacological, antioxidant, and thrombolytic potentials. GC–MS profiling identified 51 bioactive constituents, while molecular docking revealed strong affinities toward key biological targets underlying these pharmacological effects.
Azad JH, Fahad FI, Barua K, Azad SMAK, Alam S, Richi FT, Khan R, Tareq SM, Billah MM, Rana MS, Islam MN.   +10 more
europepmc   +2 more sources

Molecular Characterization of the Group A Streptococcus Virulence-Regulatory System FasBCAX. [PDF]

Mol Microbiol
The Fas system of the group A Streptococcus is comprised of three proteins (FasBCA) and a small regulatory RNA (FasX), and it represses adhesin production while also promoting the production of the spreading factor streptokinase. Here, we analyze the Fas proteins to assess how they positively regulate FasX production.
Baral S, Roshika R, Renshaw CP, Singh A, Prabhu A, Jain I, Woolsey R, Quilici D, Tal-Gan Y, Sumby P.   +9 more
europepmc   +2 more sources

Bottle Gourd (<i>Lagenaria siceraria</i>): Novel Insights Into the Biochemical Propensities of the Unexplored Cultivar. [PDF]

Scientifica (Cairo)
The fruit of Lagenaria siceraria (bottle gourd), widely consumed as a vegetable, possesses notable health benefits. This study investigated the chemical and biological profiles of the Saudi cultivar through quantitative bioactive analysis, GC‐MS characterization, and in vitro evaluation of antioxidant, antibacterial, and enzyme inhibition activities ...
Aati HY, Al-Arifi R, Ovatlarnporn C, Khan MA, Rauf A, Hassan HM, Basit A, Rao H, Rehman L, Khan KUR.   +9 more
europepmc   +2 more sources

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Medical haematology: Repositioning haematology at the centre of medicine

British Journal of Haematology, Volume 208, Issue 3, Page 845-854, March 2026.
The complementary domains of Medical Haematology and Haemato‐Oncology share a biological framework. The left panel depicts red cells, platelets, coagulation, thrombosis and innate immunity, while the right panel shows lymphoid and myeloid malignancies.
Cheng Hock Toh, Imelda Bates, Sue Pavord
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, Volume 16, Issue 2, Page 314-330, February 2026.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Successful conservative management of an intravesicular haematoma in a cat with prior urethral obstruction

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract An 8‐year‐old male neutered domestic shorthair cat was presented for the management of severe anaemia and post‐urethral obstruction care. A large intravesicular lesion, which was suspected to be a haematoma, was identified via abdominal ultrasound. This was suspected to be secondary to bleeding in the urinary tract.
Alison Robertson, Laura Cole, Karen Humm
wiley   +1 more source

Mon‐Pu (Glochidion perakense Hook.f.) as a Promising Novel Natural Source of Antithrombotic and Antioxidant Benefits

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Current evidence suggests that regular consumption of food‐functioned fruits and vegetables could reduce the risk of thrombosis. While some indigenous vegetables from Southern Thailand have been reported to exhibit anticoagulant and antiplatelet activities, their fibrinolytic and thrombolytic properties remain unexplored.
Surachai Techaoei, Muhammad Junaid, Warachate Khobjai, Suriyan Sukati, Anjali Chauhan   +4 more
wiley   +1 more source

Phytochemical Composition and Therapeutic Potential of Ludwigia adscendens: A Narrative Review

The Scientific World Journal, Volume 2026, Issue 1, 2026.
Ludwigia adscendens subsp. diffusa, an aquatic plant with an extended tradition of use in conventional healthcare, has received growing recognition for its variety of bioactive compounds. Numerous components, notably flavonoids, phenolics, tannins, alkaloids, and terpenoids, have been shown through phytochemical analyses to be responsible for the plant′
Tasnia Mahmud Easha, Faiza Hamid Jyoti, Farjana Afrin, Mahmuda Nasrin, Bhishma Karki   +4 more
wiley   +1 more source