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Streptokinase and Myocardial Infarction [PDF]
The results of several multicenter studies on the treatment of acute myocardial infarction with streptokinase are now in. Although the results are variable and, when all of the trials are considered, the impact on overall mortality is rather small, the report appearing in today's Journal suggests that a subgroup of "medium-risk" patients benefit from ...
Jay M. Sullivan
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Streptokinase is an enzyme that can break down the blood clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism.
Armi M. Chaudhari+5 more
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PLASMINOGEN ACTIVATION BY LOW MOLECULAR WEIGHT STREPTOKINASE AND FIBRIN EFFECT [PDF]
The purpose is to study the plasminogen-activating activity of 36 kDa-streptokinase fragment, influences of desAB-fibrin on this process and low molecular weight streptokinase on plasmin catalytic properties as well. The 36 kDa-fragment lacking the 63
E. I. Yusova
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Early administration of thrombolytic agents is standard for patients presenting with acute myocardial infarction (MI). Also, prolonged QT intervals indicate a higher risk for sudden death in patients with MI.
Reza Ghasemi+3 more
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Early administration of thrombolytic agents is the standard treatment and crucial for the outcome for patients presenting with acute myocardial infarction (MI). This study was conducted to evaluate the door to needle time of streptokinase administration
Reza Ghasemi+3 more
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Context Parapneumonic effusion and empyema are commonly encountered by the pulmonologist. The decision regarding management is still challenging.
Mervat A Abou Ismail+3 more
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Contribution of Streptokinase-Domains from Groups G and A (SK2a) Streptococci in Amidolytic /Proteolytic Activities and Fibrin-Dependent Plasminogen Activation: A Domain-Exchange Study [PDF]
Background: SK, a heterogeneous PA protein from groups A, C, and G streptococci (GAS, GCS, GGS, respectively) contains three structural domains (SKα, SKβ, and SK).
Maryam Rafipour+4 more
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Interaction of Streptokinase and Plasminogen [PDF]
The interaction of streptokinase (SK) with human plasminogen (HPlg) was investigated using truncated SK peptides prepared by gene cloning techniques. SK(16-414) and SK(16-378) could activate HPlg as efficiently as the authentic SK. SK(60-414), which had been preincubated with SK(1-59), could also activate HPlg. SK(91-414), SK(127-414), and SK(158-414),
Hua Lin Wu+7 more
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Background: To compare between the outcomes of streptokinase and primary PCI in acute myocardial infarction. The inappropriate treatment, misdiagnosis, contraindications of procedures can result in complications of procedures and increased mortality of ...
Zarnab Tariq, Majid Kaleem
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Antibodies to streptokinase [PDF]
Once is enough Thrombolysis is established treatment in the early management of myocardial infarction, and it reduces 35 day mortality by about a quarter.1 The GUSTO study has suggested some advantage of alteplase (rt-PA) over streptokinase with regard to early patency of the occluded coronary artery.2 In particular, GUSTO has suggested that patients ...
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