Results 31 to 40 of about 26,820 (222)
Fermentation, fractionation and purification of streptokinase by chemical reduction method
Background and Objectives: Streptokinase is used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial infarction and is commonly prepared from cultures of Streptococcus equisimilis strain H46A.
Z Karimi +4 more
doaj
Evaluation of In vivo Bioactivity of a Mutated Streptokinase
Background: Immunogenicity of Streptokinase, as a thrombolytic drug, has limited its clinical use. Elimination of the amino acid residues that are responsible for immunogenicity while don’t affect the bioactivity of streptokinase is worthy. Recently, we
Marzieh Sameni +6 more
doaj
Background & aim: Myocardial infarction is one of the most common cardiovascular diseases. Streptokinase is used in patients with myocardial infarction with ST-segment elevation.
M Behnam Moghadam +4 more
doaj
Coronary flow and hemorrhagic complications after alteplase and streptokinase administration in patients with acute myocardial infarction [PDF]
Background/Aim. Up-to-date treatment of acute myocardial infarction (AIM) has been based on as early as possible establishment of circulation in ischemic myocardium whether by the use of fibrinolythic therapy and/or urgent coronary intervention which ...
Kostić Tomislav +7 more
doaj +1 more source
Background: The risk for unsuccessful reperfusion after streptokinase therapy may be caused by the antifibrinolytic effect of platelet-derived type 1 plasminogen activator inhibitor (Pal-1) and antistreptokinase antibodies.
H Shemirani +3 more
doaj
Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
doaj +1 more source
Aim. To study effects of various streptokinase thrombolytic therapy (TLT) and following antithrombotic therapy variants on coagulation hemostasis and fibrinolysis parameters; to prove the opportunity to use reduced streptokinase doses in acute myocardial
Ya. L. Gabinsky, S. G. Kalinina
doaj
Background: GAS virulence is dependent on a functional human fibrinolytic system. Results: Functional differences between different strains of GAS streptokinases have been found.
Yueling Zhang +4 more
semanticscholar +1 more source
Abnormal chest x-ray postmyocardial infarction
Pulmonary hemorrhage is a rare complication of fibrinolytic therapy. Only a few cases are reported in the literature. We present a patient who had myocardial infarction, treated with fibrinolytic therapy and developed pulmonary hemorrhage. We discuss the
Ahmed M Abuosa +2 more
doaj +1 more source

