Results 91 to 100 of about 38,235 (184)
MetabolitesBackground/Objectives: Clavulanic acid (CA) is produced by cell suspension cultures of Streptomyces clavuligerus ATCC 27064, and is widely used as a beta-lactamase inhibitor to combat antibiotic resistance.
Luisa F. Patiño +4 more
doaj +1 more source
Angewandte Chemie, Volume 136, Issue 6, February 5, 2024.19‐nor‐Geranylgeranyldiphosphat mit entfernter Methylgruppe wurde synthetisiert und mit 20 Diterpensynthasen in Diterpenanaloga umgewandelt. In einigen Fällen wurden nur die Desmethylderivate der natürlichen Enzymprodukte erhalten, bei einigen Enzymen wurde jedoch eine dramatische Veränderung der Reaktivität beobachtet. Die neu eröffneten Reaktionswege
Kizerbo A. Taizoumbe +2 more
wiley +1 more source
, 2010 Streptomyces clavuligerus is an important industrial strain that produces a number of antibiotics, including clavulanic acid and cephamycin C. A high-quality draft genome sequence of the S.
Michael A. Fischbach +10 more
core +1 more source
Biological Journal of Microorganism, 2014 Introduction : Clavulanic acid is a major β-lactam antibiotic which is produced by Streptomyces clavuligerus. Clavulanic acid is used in combination of strong but sensitive to β-lactamase antibiotics.
Maryam Kay +2 more
doaj
Angewandte Chemie International Edition, Volume 63, Issue 6, February 5, 2024.19‐nor‐Geranylgeranyldiphosphate (with a methyl group removed) has been synthesised and converted into diterpene analogues with 20 diterpene synthases. In some cases only the desmethyl derivatives of the natural enzyme products were obtained, but with several enzymes a dramatic change in the reactivity was observed.
Kizerbo A. Taizoumbe +2 more
wiley +1 more source
, 2008 Aims: This study aims to establish whether commercially available food oils can be used by Streptomyces clavuligerus as sole carbon sources for growth and clavulanic acid production. Methods and results: Batch cultures in bioreactors showed that Strep.
Avignone-Rossa, C.A. +2 more
core +4 more sources
Microbial Biotechnology, Volume 17, Issue 1, January 2024.Our findings clarify the molecular mechanisms underlying functions of regulatory proteins AfsR and AfsS in Streptomyces antibiotic production and development, which are based on direct control of their target genes associated with these two important biological processes.
Yi Hao +3 more
wiley +1 more source
Characterization and expression of the arginine biosynthesis gene cluster of Streptomyces clavuligerus [PDF]
Revista continuada por Microbial Physiology[EN] A cluster of genes argCJBDRGH containing most of the arginine biosynthesis genes has been found in Streptomyces clavuligerus after sequencing a 8.3 kb DNA region containing overlapping sequences of two DNA ...
Rodríguez García, Antonio +4 more
core
Molecular Analysis of the Clavulanic Acid Regulatory Gene Isolated from an Iranian Strain of Streptomyces Clavuligerus, PTCC 1709 [PDF]
Cell Journal, 2011 Objective: The clavulanic acid regulatory gene (claR) is in the clavulanic acid biosyntheticgene cluster that encodes ClaR. This protein is a putative regulator of the late steps ofclavulanic acid biosynthesis.
Hasan Korbekandi +4 more
doaj
Dyna, 2018 The clinical and industrial importance of clavulanic acid (CA) promotes the search for novel strategies to boost productivity at lower costs. In this contribution, the production of CA was evaluated in two reference strains of Streptomyces clavuligerus ...
Laura Pinilla +4 more
doaj +1 more source