Results 71 to 80 of about 1,344 (153)

Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus

Brazilian Archives of Biology and Technology, 2005
The aim of the present work was to compare CA production in continuous culture with and without cell recycling and in batch process by Streptomyces clavuligerus.
Álvaro Baptista-Neto, Juliana Conceição Teodoro, Luiz Claudio Macedo Cassiano Filho, Alberto Colli Badino, Carlos Osamu Hokka   +4 more
doaj   +1 more source

Crystal structure of a short‐chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid

Acta Crystallographica Section F, Volume 80, Issue 12, Page 348-355, December 2024.
The structure of B. cenocepacia short‐chain dehydrogenase/reductase (SDR) in complex with NADP+ and benzoic acid is presented. Analysis of the structure reveals a distinctive active‐site architecture, suggesting that this protein is part of the divergent SDR subgroup.Burkholderia cenocepacia is an opportunistic human pathogen that can cause lethal ...
Kafi K. J. Belfon, Olive Beyer, Jan Abendroth, David M. Dranow, Donald D. Lorimer, Ariel Abramov, Yazmine Latimore, Connor Hamilton, Aniah Dawkins, Isabella Hinojosa, Xavier Martinez, Sofia Mirabel, Miriam Duncan, Reagan Womack, Lillian Hicks, Zachary R. Turlington, Thomas E. Edwards, Andrew T. Torelli, Katherine A. Hicks, Jarrod B. French   +19 more
wiley   +1 more source

Machine‐Learning Analysis of Streptomyces coelicolor Transcriptomes Reveals a Transcription Regulatory Network Encompassing Biosynthetic Gene Clusters

Advanced Science, Volume 11, Issue 41, November 6, 2024.
Streptomyces produces pharmaceutically important secondary metabolites. To harness their genetic potential with understanding transcriptional regulation, independent component analysis is conducted on 454 transcriptomic profiles of Streptomyces coelicolor, revealing 117 independently modulated groups of genes (iModulons).
Yongjae Lee, Donghui Choe, Bernhard O. Palsson, Byung‐Kwan Cho   +3 more
wiley   +1 more source

Bioactive Streptomycetes: A Powerful Tool to Synthesize Diverse Nanoparticles With Multifarious Properties

Journal of Basic Microbiology, Volume 64, Issue 9, September 2024.
ABSTRACT Nanobiotechnology has gained significant attention due to its capacity to generate substantial benefits through the integration of microbial biotechnology and nanotechnology. Among microbial organisms, Actinomycetes, particularly the prominent genus Streptomycetes, have garnered attention for their prolific production of antibiotics ...
Muhammad Sultan Anjum, Shazia Khaliq, Neelma Ashraf, Munir Ahmad Anwar, Kalsoom Akhtar   +4 more
wiley   +1 more source

Data of clavulanic acid and clavulanate-imidazole stability at low temperatures

Data in Brief, 2019
Clavulanic acid (CA) is a β-lactam antibiotic with a strong inhibitory effect on β-lactamase enzymes. CA is produced in submerged cultures by the filamentous Gram-positive bacterium Streptomyces clavuligerus (S. clavuligerus).
David Gómez-Ríos, Howard Ramírez-Malule, Peter Neubauer, Stefan Junne, Rigoberto Ríos-Estepa   +4 more
doaj   +1 more source

Efficient plasmid transformation of the beta-lactam producer Streptomyces clavuligerus [PDF]

Applied and Environmental Microbiology, 1987
The conditions for optimal formation and regeneration of protoplasts of Streptomyces clavuligerus were established. The optimal temperature for regeneration of protoplasts and for transformation was 26 degrees C in three different regeneration media. The best efficiency of transformation was obtained with 40% polyethylene glycol 1000.
M, Garcia-Dominguez, J F, Martin, B, Mahro, A L, Demain, P, Liras   +4 more
openaire   +2 more sources

Activity of Actinomycetes Isolated from Mangrove Segara Anakan Cilacap toward Methicillin-resistant Staphylococcus aureus (MRSA)

Jurnal Kimia Sains dan Aplikasi, 2020
Methicillin-resistant Staphylococcus aureus (MRSA) is a major health concern because it causes numerous infections in both healthcare facilities and communities.
Ari Asnani, Eva Luviriani, Oedjijono Oedjijono   +2 more
doaj   +1 more source

Enzymatic Synthesis of Diterpenoids from iso‐GGPP III: A Geranylgeranyl Diphosphate Analog with a Shifted Double Bond

Chemistry – A European Journal, Volume 30, Issue 8, February 7, 2024.
The geranylgeranyl diphosphate (GGPP) analog iso‐GGPP III with a shifted double bond was synthesized and enzymatically converted with six diterpene synthases. The main products were isolated from the often complex product mixtures and structurally characterized, revealing, in several cases, the formation of compounds with novel skeletons that can be ...
Heng Li, Jeroen S. Dickschat
wiley   +1 more source

Increase of Clavulanic acid production by using recombinant Streptomyces clavuligerus strain including claR gene

Biological Journal of Microorganism, 2014
Introduction : Clavulanic acid is a major β-lactam antibiotic which is produced by Streptomyces clavuligerus. Clavulanic acid is used in combination of strong but sensitive to β-lactamase antibiotics.
Maryam Kay, zohreh Hojati, Majid Motovali-Bashi   +2 more
doaj  

Morphology and viability analysis of Streptomyces clavuligerus in industrial cultivation systems [PDF]

Bioprocess and Biosystems Engineering, 2004
The effects of varying inoculum age and production scale upon the morphology and viability of Streptomyces clavuligerus were studied by analyzing visible and fluorescent light images acquired throughout pilot-plant and pre-industrial scale fermentations.
Pinto, L., Vieira, L., Pons, Marie-Noëlle, Fonseca, M., Menezes, J.   +4 more
openaire   +2 more sources