Results 81 to 90 of about 38,235 (184)
Carbon Catabolite Regulation of Cephalosporin Production in Streptomyces clavuligerus [PDF]
Antimicrobial Agents and Chemotherapy, 1978 Cephalosporin production by Streptomyces clavuligerus is regulated by some type of carbon catabolite control. Increasing concentrations of preferred carbon sources, such as glycerol and maltose, decreased production of the antibiotics.
Y, Aharonowitz, A L, Demain
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Acta Crystallographica Section F, Volume 80, Issue 12, Page 348-355, December 2024.The structure of B. cenocepacia short‐chain dehydrogenase/reductase (SDR) in complex with NADP+ and benzoic acid is presented. Analysis of the structure reveals a distinctive active‐site architecture, suggesting that this protein is part of the divergent SDR subgroup.Burkholderia cenocepacia is an opportunistic human pathogen that can cause lethal ...
Kafi K. J. Belfon +19 more
wiley +1 more source
A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus [PDF]
, 2013 Attine ants are dependent on a cultivated fungus for food and use antibiotics produced by symbiotic Actinobacteria as weedkillers in their fungus gardens. Actinobacterial species belonging to the genera Pseudonocardia, Streptomyces and Amycolatopsis have
Brearley, Charles +6 more
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Advanced Science, Volume 11, Issue 41, November 6, 2024.Streptomyces produces pharmaceutically important secondary metabolites. To harness their genetic potential with understanding transcriptional regulation, independent component analysis is conducted on 454 transcriptomic profiles of Streptomyces coelicolor, revealing 117 independently modulated groups of genes (iModulons).
Yongjae Lee +3 more
wiley +1 more source
Journal of Basic Microbiology, Volume 64, Issue 9, September 2024.ABSTRACT Nanobiotechnology has gained significant attention due to its capacity to generate substantial benefits through the integration of microbial biotechnology and nanotechnology. Among microbial organisms, Actinomycetes, particularly the prominent genus Streptomycetes, have garnered attention for their prolific production of antibiotics ...
Muhammad Sultan Anjum +4 more
wiley +1 more source
Data of clavulanic acid and clavulanate-imidazole stability at low temperatures
Data in Brief, 2019 Clavulanic acid (CA) is a β-lactam antibiotic with a strong inhibitory effect on β-lactamase enzymes. CA is produced in submerged cultures by the filamentous Gram-positive bacterium Streptomyces clavuligerus (S. clavuligerus).
David Gómez-Ríos +4 more
doaj +1 more source
Jurnal Kimia Sains dan Aplikasi, 2020 Methicillin-resistant Staphylococcus aureus (MRSA) is a major health concern because it causes numerous infections in both healthcare facilities and communities.
Ari Asnani +2 more
doaj +1 more source
SYNTHESIS OF BENZYLPENICILLIN BY CELL-FREE EXTRACTS FROM STREPTOMYCES CLAVULIGERUS
The Journal of Antibiotics, 1986 Cell-free enzyme concentrates from Streptomyces clavuligerus were found to convert phenylacetyl-L-cysteinyl-D-valine (PCV) directly into benzylpenicillin when incubated under reaction conditions which support the activity of isopenicillin N synthetase.
S E, Jensen +4 more
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Chemistry – A European Journal, Volume 30, Issue 8, February 7, 2024.The geranylgeranyl diphosphate (GGPP) analog iso‐GGPP III with a shifted double bond was synthesized and enzymatically converted with six diterpene synthases. The main products were isolated from the often complex product mixtures and structurally characterized, revealing, in several cases, the formation of compounds with novel skeletons that can be ...
Heng Li, Jeroen S. Dickschat
wiley +1 more source
Streptomyces clavuligerus proteomiği-optimizasyon [PDF]
, 2015 TÜBİTAK KBAG15.05.2015Streptomyces clavuligerus, sefamisin C antibiyotiği, bir beta laktamaz inhibitörü olan klavulanik asit ve anti-fungal ve antibakteriyel özelliğe sahip başka klavam bileşikleri üretmektedir.
Çırçır Hatıl, Ayça +2 more
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