Results 121 to 130 of about 151,903 (303)
Effect of streptozotocin on foetal lambs in mid-pregnancy
, 1982 Streptozotocin was administered to 11 foetal lambs in utero at 70–85 days of gestation. Four of the foetuses survived and, when delivered at 134–142 days, exhibited significant growth retardation of the trunk and delayed osseous maturation in limb bones.
Brinsmead, M. W., Thorburn, G. D.
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Association of the TLR4 signaling pathway in the retina of streptozotocin-induced diabetic rats
, 2015 Diabetic retinopathy is severe damage to the retina caused by complications of diabetes, and is the prevailing cause of blindness. Accumulating evidence from both animal models and humans suggests that the inflammatory process plays a key role in the ...
Li, Qian +7 more
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Effects of Resveratrol on the Kidney in Rats with Streptozotocin Induced Diabetic Nephropathy [PDF]
Objective: Diabetic nephropathy is one of the most significant causes of end-stage renal failure and is a common microvascular complication of diabetes (D).
Aydan Babül +13 more
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Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis
iNew Medicine, EarlyView.This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang +3 more
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, 2015 Chuanwei Xin, Zhongni Xia, Cheng Jiang, Mengmeng Lin, Gonghua Li Department of Pharmacy, Zhejiang Academy of Traditional Chinese Medicine, Tongde Hospital of Zhejiang Province, Hangzhou, People’s Republic of China Background: Diabetic nephropathy
Li G, Xia Z, Xin C, Jiang C, Lin M
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Journal of Applied Toxicology, EarlyView.ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
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, 2018 Hongxia Zhang,1 Yanlan Yang,2 Yanqin Wang,1 Baodong Wang,1 Rongshan Li1 1Department of Nephrology, 2Department of Endocrinology, Affiliated People’s Hospital of Shanxi Medical University, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi,
Yang Y, Wang B, Zhang H, Li R, Wang Y
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JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
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, 1993 Gangliosides have been shown to modulate autoimmune phenomena in experimental diabetes. The effects of a pancreatic ganglioside preparation or of a commercial brain ganglioside mixture on the insulitis and blood glucose levels in the low-dose ...
Tiberti C. +8 more
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JSFA reports, EarlyView.Abstract The dietary and lifestyle practices have predominantly compromised human health, which are influenced by modernization and industrialization. Hypercholesterolemia, caused by the consumption of fatty and fried foods and a sedentary lifestyle, is a major modifiable risk factor for cardiovascular disease and commonly coexists with obesity ...
Muhammad Usman Khalid +8 more
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