Results 141 to 150 of about 181,208 (343)

Synergistic Effect of Hesperidin, Acarbose, and Exercise Combination on Neuroinflammation and Neurochemical Alterations in Diabetic Encephalopathy Rat Model

Food Chemistry International, EarlyView.
Diabetic encephalopathy (DME) impairs neurobehavior, neurochemicals, oxidative stress, and inflammation. This study evaluated the effects of hesperidin (HSP), exercise (EX), and acarbose (ACA) alone or combined on diabetic rats. Treatments reduced AChE, BChE, ACE, arginase, ATPDase, 5′‐nucleotidase, ADA, LDH, TBARS, and ROS, while increasing IL‐10, SOD,
Idowu Sunday Oyeleye, Olajide Raymond Ojo, Taiwo Olawale Adeleke, Adeyinka Sunday Ajeigbe, Mercy Gladys Tenywa, Oboh Ganiyu   +5 more
wiley   +1 more source

Serum lipid peroxidation and leptin levels in male and female type 2 diabetic patients in Gorgan (south east of Caspian Sea), Iran [PDF]

, 2009
Background: The aim of the present study was to determinate the possible relationship between serum leptin and lipid peroxidation in male and female type 2 diabetic patients in Gorgan, Iran.
Badeleh, M.T., Marjani, A., Veghari, G.
core  

Functional Bread From Bambara Groundnut and Orange Peel Attenuates Hyperglycemia and Oxidative Stress in a High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetes Rat Model

Food Chemistry International, EarlyView.
This study evaluated Bambara groundnut–wheat composite bread fortified with orange peel in diabetic rats. Diets significantly lowered blood glucose, inhibited α‐glucosidase and α‐amylase, and boosted antioxidant enzymes compared to controls. Results emphasize BG‐based functional foods' potential to help manage type 2 diabetes through regulation of ...
S. O. Oguntuase, O. W. Fasakin, I. S. Oyeleye, G. Oboh   +3 more
wiley   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Hypoglychemic activity of Moringa oleifera extract in streptozotocin-induced diabetic rats

Acta Biochimica Indonesiana
Background: Diabetes mellitus, particularly Type 2 (T2DM), is a global health concern characterized by high blood glucose levels and insulin resistance. Objective: This study aims to explore the hypoglycemic potential of M.
Rabiatul Adawiyah, Tri Setyawati, Rahma Badaruddin, Listawati   +3 more
doaj   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

The Effect of Chronic Oral Administration of Withania Somnifera Root on Learning and Memory in Diabetic Rats Using Passive Avoidance Test

پزشکی بالینی ابن سینا, 2006
Introduction & Objective: Diabetes mellitus (especially type I) is accompanied with disturbances in learning, memory, and cognitive skills in the human society and experimental animals.
Mehrdad Roghani, Tourandokht Baluchnejadmojarad, Mohsen Khalili, Seyyedeh Fatemeh Mahdavi Salimi   +3 more
doaj  

Nephroprotective and Anti-Diabetic Potential of Beta vulgaris L. Root (Beetroot) Methanolic Extract in a Rat Model of Type 2 Diabetes Mellitus

Medicina
Background and Objectives: Diabetes mellitus is a chronic metabolic disease associated with several complications, including that of kidney disease. Plant-based dietary products have shown promise in mitigating these effects to improve kidney function ...
Laila Naif Al-Harbi, Ghedeir M. Alshammari, Ghalia Shamlan, Manal Abdulaziz Binobead, Sahar Abdulaziz AlSedairy, Doha M. Al-Nouri, Shaista Arzoo, Mohammed Abdo Yahya   +7 more
doaj   +1 more source

Early matrine intervention of gut microbiota for type 2 diabetes prevention

iMetaOmics, EarlyView.
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun, Hujie Lyu, Hailang Xu, Xianjin Qin, Wei Li   +4 more
wiley   +1 more source

Increased Serum Superoxide Dismutase and Catalase Activities in Streptozotocin-Induced Diabetic Rats

Medical Laboratory Journal, 2014
Background and Objective: One of the diabetes complications is the tissue damage caused by the imbalance of oxidants and antioxidants (oxidative stress).
E Kharazi-Nejad, A Nakhaee, M Taheri
doaj