Results 11 to 20 of about 450,357 (249)

Understanding the mechanisms of lung mechanical stress [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2006
Physical forces affect both the function and phenotype of cells in the lung. Bronchial, alveolar, and other parenchymal cells, as well as fibroblasts and macrophages, are normally subjected to a variety of passive and active mechanical forces associated with lung inflation and vascular perfusion as a result of the dynamic nature of lung function. These
Garcia, C. S. N. B.   +5 more
openaire   +7 more sources

Mechanisms of stress in the brain [PDF]

open access: yesNature Neuroscience, 2015
The brain is the central organ involved in perceiving and adapting to social and physical stressors via multiple interacting mediators, from the cell surface to the cytoskeleton to epigenetic regulation and nongenomic mechanisms. A key result of stress is structural remodeling of neural architecture, which may be a sign of successful adaptation ...
Bruce S McEwen   +6 more
openaire   +4 more sources

Mechanism of Oxidative Stress in Neurodegeneration [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2012
Biological tissues require oxygen to meet their energetic demands. However, the consumption of oxygen also results in the generation of free radicals that may have damaging effects on cells. The brain is particularly vulnerable to the effects of reactive oxygen species due to its high demand for oxygen, and its abundance of highly peroxidisable ...
Gandhi, S, Abramov, AY
openaire   +4 more sources

Interaction of Mechanical Heterogeneity and Residual Stress on Mechanical Field at Crack Tips in DMWJs

open access: yesScience and Technology of Nuclear Installations, 2022
The interaction between the mechanical heterogeneity and the residual stress in dissimilar metal welded joints (DMWJs) leads to a complex mechanical field of crack tips, which strongly affects stress corrosion cracking (SCC) behaviors.
Yubiao Zhang   +6 more
doaj   +1 more source

Influence of thermal-mechanical stress on the insulation system of a low voltage electrical machine [PDF]

open access: yesArchives of Electrical Engineering, 2021
Varying ohmic loss in the winding of electrical machines, which are operated at various operating points, results in temperature changes during operation.
Liguo Yang, Florian Pauli, Kay Hameyer
doaj   +1 more source

Regular Mechanical Stimuli Enhanced Tolerance to Salinity Stress in Glycine max L. Seedlings

open access: yesJournal of Tropical Life Science, 2023
Regular touch treatment leads to plant adaptations that enhances mechanical strength. In many crop plants these adaptations result in cross-tolerance to biotic stress caused by bacterial or fungal infection and abiotic stress conditions like salinity or ...
Juhika Patel   +2 more
doaj   +1 more source

Destabilization of Indomethacin-Paracetamol Co-Amorphous Systems by Mechanical Stress

open access: yesPharmaceutics, 2023
Using co-amorphous systems (CAMS) has shown promise in addressing the challenges associated with poorly water-soluble drugs. Quench-cooling is a commonly used CAMS preparation method, often followed by grinding or milling to achieve a fine powder that is
Rong Di, Thomas Rades, Holger Grohganz
doaj   +1 more source

Stress mechanisms in hypertension [PDF]

open access: yesPostgraduate Medical Journal, 1986
Summary Recent studies of stress mechanisms in hypertension have focussed on the cardiovascular and neuroendocrine reactions to challenging or threatening psychosocial stimuli. Fixed hypertension may develop in some animal models following chronic exposure to psychosocial conflict.
openaire   +3 more sources

Whole Transcriptome Mapping Identifies an Immune- and Metabolism-Related Non-coding RNA Landscape Remodeled by Mechanical Stress in IL-1β-Induced Rat OA-like Chondrocytes

open access: yesFrontiers in Genetics, 2022
Background: Osteoarthritis (OA) is a common degenerative joint disease. The aims of this study are to explore the effects of mechanical stress on whole transcriptome landscape and to identify a non-coding transcriptome signature of mechanical stress ...
Jiaming Zhang   +8 more
doaj   +1 more source

Finite element analysis of mechanical stress in in-wheel motor [PDF]

open access: yesArchives of Electrical Engineering, 2022
When the in-wheel motor is working, it will be affected by gravity, centrifugal force and electromagnetic force. These three kinds of mechanical loads will affect the mechanical stress characteristics of the in-wheel motor, and then affect the ...
Jie Xu
doaj   +1 more source

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