Results 61 to 70 of about 450,357 (249)

Effect of Lamination Angle and Thickness on Analysis of Composite Plate Under Thermo Mechanical Loading

Journal of Mechanical Engineering, 2017
Analytical formulation and solution of stress analysis of composite plate subjected to thermo mechanical loading for various ply orientation and thickness of lamina are studied.
Choudhury Arnab, Mondal Samar Chandra, Sarkar Susenjit   +2 more
doaj   +1 more source

Simulation Study on Local and Integral Mechanical Quantities at Single Trabecular Level as Candidates of Remodeling Stimuli

Journal of Biomechanical Science and Engineering, 2006
Mechanical quantities at the microstructural level play important roles as stimuli of trabecular bone remodeling by which cancellous bone maintains and adapts its trabecular structure to the mechanical environment.
Ken-ichi TSUBOTA, Taiji ADACHI
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Influences of lithology on in-situ stress field in low permeability reservoirs in Bonan Oilfield, Bohai Bay Basin, China

Petroleum Exploration and Development, 2019
The differences of rock mechanical properties were analyzed based on triaxial compression test in low permeability reservoirs of the Bonan Oilfield. Through the analysis of reservoir mechanics, the influence mechanisms of different mechanical properties ...
Zhipeng LI, Xiantai LIU, Yong YANG, Lixia BU   +3 more
doaj  

Periodic mechanical stress activates MEK1/2-ERK1/2 mitogenic signals in rat chondrocytes through Src and PLCγ1

Brazilian Journal of Medical and Biological Research, 2011
The mitogenic effects of periodic mechanical stress on chondrocytes have been studied extensively but the mechanisms whereby chondrocytes sense and respond to periodic mechanical stress remain a matter of debate.
Kewei Ren, Yimin Ma, Yumin Huang, Wenwei Liang, Feng Liu, Qing Wang, Weiding Cui, Zhengyu Liu, Guoyong Yin, Weimin Fan   +9 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Study on stress change law of coal body permeability improvement by mechanical reaming

Meikuang Anquan
Mechanical reaming, as a new type of coal seam pressure relief and permeability enhancement measure, can be widely applied to low permeability gas coal seams. In order to investigate the stress evolution law of mechanical reaming, the stress distribution
Haichun WANG, Dongji LEI, Zhenhua DAI, Jie QIN   +3 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Effect of plasma sericin glutaraldehyde treatments on the low stress mechanical properties of micro denier polyester/cotton blended fabric. [PDF]

Sci Rep, 2022
Rajalakshmi M, Kubera Sampath Kumar S, Vasanth Kumar D, Siva Jagadish Kumar M, Prakash C.   +4 more
europepmc   +1 more source