Results 71 to 80 of about 1,733,478 (299)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Statistical Mechanics of Stress Transmission in Disordered Granular Arrays
We give a statistical-mechanical theory of stress transmission in disordered arrays of rigid grains with perfect friction. Starting from the equations of microscopic force and torque balance we derive the fundamental equations of stress equilibrium.
B. Miller +10 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Correlating Cell Shape and Cellular Stress in Motile Confluent Tissues
Collective cell migration is a highly regulated process involved in wound healing, cancer metastasis and morphogenesis. Mechanical interactions among cells provide an important regulatory mechanism to coordinate such collective motion.
Bi, Dapeng +5 more
core +1 more source
Thermo-mechanical FE model with memory effect for 304L austenitic stainless steel presenting microstructure gradient [PDF]
The main purpose of this study is to determine, via a three dimensions Finite Element analysis (FE), the stress and strain fields at the inner surface of a tubular specimen submitted to thermo-mechanical fatigue.
Bompard, Philippe +5 more
core +6 more sources
Plants Stress: Salt Stress and Mechanisms of Stress Tolerance
A diverse combination of biotic and abiotic pressures makes up the environment that plants naturally inhabit. These pressures cause similarly complicated responses in plants. The purpose of the review is to critically evaluate the effects of various stress stimuli on higher plants with an emphasis on the typical and distinctive dose-dependent responses
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Development of reliability prediction technique for semiconductor diodes [PDF]
New fundamental technique of reliability prediction for semiconductor diodes based on realistic mathematical models can be applied to component failure rate prediction including mechanical degradation, electrical degradation, environmental stress factors,
Ryerson, C. M.
core +1 more source
Local Optical Probe of Motion and Stress in a multilayer graphene NEMS
Nanoelectromechanical systems (NEMSs) are emerging nanoscale elements at the crossroads between mechanics, optics and electronics, with significant potential for actuation and sensing applications.
A Castro Neto +36 more
core +3 more sources
Cell contraction induces long-ranged stress stiffening in the extracellular matrix [PDF]
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains largely unknown ...
Broedersz, Chase P. +7 more
core +2 more sources

