Results 61 to 70 of about 1,971,553 (284)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Effects of Stress Mindset Interventions on University Students\u27 Health and Functioning [PDF]

, 2019
In modern society, the overwhelming cultural narrative proclaims that stress is detrimental to health and should be limited and avoided at all costs.
Fate, Abigail
core   +1 more source

Atomic Force Microscopy of height fluctuations of fibroblast cells [PDF]

, 2002
We investigated the nanometer scale height fluctuations of 3T3 fibroblast cells with the atomic force microscope (AFM) under physiological conditions. Correlation between these fluctuations and lateral cellular motility can be observed.
A. Czirók, B. Hegedös, Bálint Szabó, C. Pasternak, C. Rotsch, C.A. Shönenberger, Ch. Rotsch, Ch.S. Peskin, Dávid Selmeczi, E. Henderson, Emília Madarász, F. Jülicher, G.G. Borisy, H. Chen, H. Haga, H.J. Butt, J. Domke, K. Yasuda, L. Mahadevan, L.M. Machesky, M. Bornens, M. Lekka, M.U. Ehrengruber, Noémi Rozlosnik, O.J. Pletjushkina, S.W. Schneider, T. Duke, T.A.J. Duke, U.G. Hofmann, V. Parpura, Zs. Környei, Zsuzsanna Környei   +31 more
core   +2 more sources

Physiological Stress in Laying Hens

Poultry Science, 2006
Stress responses in laying hens were mediated by continuous infusion of adrenocorticotropin (ACTH) via osmotic pumps. The ACTH was dissolved in saline solution (0.85%), and each pump delivered 8 IU of ACTH per kilogram of BW per day at the rate of 1 microL/h for 7 d. Control hens received pumps loaded with saline. Measurements were made at 6 d postpump
J Odihambo, Mumma, J P, Thaxton, Y, Vizzier-Thaxton, W L, Dodson   +3 more
openaire   +2 more sources

Stress detection by means of stress physiological template [PDF]

2011 Third World Congress on Nature and Biologically Inspired Computing, 2011
This paper describes a stress detection system based on fuzzy logic and two physiological signals: Galvanic Skin Response and Heart Rate. Instead of providing a global stress classification, this approach creates an individual stress templates, gathering the behaviour of individuals under situations with different degrees of stress. The proposed method
Santos Sierra, Alberto de, Sánchez Ávila, María del Carmen, Bailador del Pozo, Gonzalo, Guerra Casanova, Javier   +3 more
openaire   +2 more sources

Impact of 24 h shifts on urinary catecholamine in emergency physicians: a cross-over randomized trial

Scientific Reports
24-h shift (24 hS) exposed emergency physicians to a higher stress level than 14-h night shift (14 hS), with an impact spreading on several days. Catecholamines are supposed to be chronic stress biomarker.
Frédéric Dutheil, Alicia Fournier, Christophe Perrier, Damien Richard, Marion Trousselard, George Mnatzaganian, Julien S. Baker, Reza Bagheri, Martial Mermillod, Maelys Clinchamps, Jeannot Schmidt, Jean-Baptiste Bouillon-Minois   +11 more
doaj   +1 more source

Psychosocial well-being index and sick leave in the workplace: a structural equation modeling of Wittyfit data

Frontiers in Psychology
BackgroundPsychosocial well-being, which assesses emotional, psychological, social, and collective well-being, could help measure risk and duration of sick leave in workers.ObjectiveThis study aims to build a structural equation model of a psychosocial ...
Rémi Colin-Chevalier, Bruno Pereira, Samuel Dewavrin, Thomas Cornet, Julien Steven Baker, Frédéric Dutheil   +5 more
doaj   +1 more source

Cytoprotective functions of amyloid precursor protein family members in stress signaling and aging [PDF]

, 2013
Poster presentation: Molecular Neurodegeneration: Basic biology and disease pathways Cannes, France. 10-12 September 2013. Background: The amyloid precursor protein (APP) is processed via two different metabolic pathways: the amyloidogenic and the non ...
Chang, Steffi, Kundu, Arpita, Kögel, Donat, Röhner, Nelli, Zymny, Andreas   +4 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Plant Growth and Stress Physiology

, 2021
Mitra, A. et al. -- Gupta, D.K.; Palma, J.M. (eds)
Mitra, A., Bek, N.
openaire   +2 more sources