Results 41 to 50 of about 2,700,982 (237)

Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]

open access: yes, 1990
In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin   +3 more
core   +1 more source

Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]

open access: yes, 1964
For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
core   +1 more source

Foxo3 is required for the regulation of oxidative stress in erythropoiesis [PDF]

open access: yesJournal of Clinical Investigation, 2007
Erythroid cells accumulate hemoglobin as they mature and as a result are highly prone to oxidative damage. However, mechanisms of transcriptional control of antioxidant defense in erythroid cells have thus far been poorly characterized. We observed that animals deficient in the forkhead box O3 (Foxo3) transcription factor died rapidly when exposed to ...
Marinković, Dragan   +6 more
openaire   +3 more sources

The maturation of reticulocytes. I. Following introduction of reticulocytes into polycythemic and normocythemic animals [PDF]

open access: yes, 1975
Investigations were conducted on the life-span of "stress" reticulocytes and the fate of the early denucleated large-sized reticulocytes in circulating blood.
Shimada, Atsuko
core   +1 more source

Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output

open access: yesHaematologica, 2020
Massive expansion of erythroid progenitor cells is essential for surviving anemic stress. Research towards understanding this critical process, referred to as stress-erythropoiesis, has been hampered due to lack of specific marker-combinations enabling ...
Sofie Singbrant   +4 more
doaj   +1 more source

CD169-CD43 interaction is involved in erythroblastic island formation and erythroid differentiation

open access: yesHaematologica, 2023
CD169, a specific marker for macrophages, is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family which acts as an adhesion molecule implicated in cell–cell interaction via sialylated glycoconjugates.
Jian Bai   +13 more
doaj   +1 more source

Stress erythropoiesis: new signals and new stress progenitor cells [PDF]

open access: yesCurrent Opinion in Hematology, 2011
Acute anemic stress induces a physiological response that includes the rapid development of new erythrocytes. This process is referred to as stress erythropoiesis, which is distinct from steady state erythropoiesis. Much of what we know about stress erythropoiesis comes from the analysis of murine models.
Robert F, Paulson   +2 more
openaire   +2 more sources

SAMD14 Mechanisms in Stress Erythropoiesis [PDF]

open access: yes, 2023
Red blood cells (RBCs) essential for tissue oxygenation are generated by the process of erythropoiesis. Any decrease in the RBCs or the oxygen-carrying molecule hemoglobin leads to anemia, affecting nearly 1.62 billion people worldwide.
Ray, Suhita
core  

Single-cell RNA seq analysis of erythroid cells reveals a specific sub-population of stress erythroid progenitors

open access: yesHematology, 2023
Background : Erythroid cells play important roles in hemostasis and disease. However, there is still significant knowledge gap regarding stress erythropoiesis.Methods : Two single-cell RNAseq datasets of erythroid cells on GEO with accession numbers ...
Hanneda A. Fomukong   +9 more
doaj   +1 more source

Stressed about erythropoiesis: EBI macrophages [PDF]

open access: yesBlood, 2018
In this issue of Blood, Liao et al report that anemic stress induces CCL2 production in the spleen, which recruits monocytes that associate with stress erythroid progenitors (SEPs) and differentiate into central macrophages to create erythroblastic islands (EBIs ...
openaire   +2 more sources

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