Results 291 to 300 of about 129,858 (349)

PKA regulates stress granule maturation to allow timely recovery after prolonged starvation

Kroschwald S, Uliana F, Wilson-Zbinden C, Timofiiva A, Zhou J, Lee SS, Gillet L, Zanella M, Othman A, Mezzenga R, Peter M.   +10 more
europepmc   +1 more source

Aβ₄₂ induces stress granule formation via PACT/PKR pathway. [PDF]

Sci Rep
Ramasamy VS, Nathan ABP, Choi MC, Kim SH, Ohn T.   +4 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Stress Granule Induction in Rat Retinas Damaged by Constant LED Light. [PDF]

Invest Ophthalmol Vis Sci
Benedetto MM, Malcolm M, Bruera MG, Penazzi LG, Guido ME, Contín MA, Garbarino-Pico E.   +6 more
europepmc   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

Exploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren, Zhaoxu Wu, Min Li, Yaqin Du, Hong Zhou, Yazhu Quan, Mengyao Xiong, Yiming Wang, Zhiwei Qiu, Shuai Zhu, Xiaowei Li, Jinzhao He, Cai Gao, Hui Cai, Tingting Li, Baoxue Yang   +15 more
wiley   +1 more source

µMap proximity labeling in living cells reveals stress granule disassembly mechanisms. [PDF]

Nat Chem Biol
Pan CR, Knutson SD, Huth SW, MacMillan DWC.   +3 more
europepmc   +1 more source

Reviewer #1 (Public Review): Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress

openalex   +1 more source

Protocol for the Preparation of Polyphenols‐Polysaccharide Nanoparticles

Food Chemistry International, EarlyView.
ABSTRACT Polyphenols, natural compounds abundantly distributed in plants, possess potent antioxidant and anti‐inflammatory activities and hold promising potential in cardiovascular protection and the management of metabolic disorders. Nevertheless, their intrinsic instability and low bioavailability severely constrain their practical and large‐scale ...
Chenxu Bao, Boqian He, Siyu Han, Jingying Liu, Jia Yan, Chunlin Li, Qian Wu   +6 more
wiley   +1 more source

Human DBR1 deficiency impairs stress granule-dependent PKR antiviral immunity. [PDF]

J Exp Med
Ru S, Tang S, Xu H, Yin J, Guo Y, Song L, Jin Z, Lee D, Chan YH, Chen X, Buerer L, Fairbrother W, Jia W, Casanova JL, Zhang SY, Gao D.   +15 more
europepmc   +1 more source