Results 31 to 40 of about 128,882 (297)
Plant Stress Granules: Trends and Beyond [PDF]
Frontiers in Plant Science, 2021 Stress granules (SGs) are dynamic membrane-less condensates transiently assembled through liquid–liquid phase separation (LLPS) in response to stress. SGs display a biphasic architecture constituted of core and shell phases. The core is a conserved SG fraction fundamental for its assembly and consists primarily of proteins with intrinsically disordered
Maruri Lopez, Israel +3 more
openaire +4 more sources
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner
Life Science Alliance, 2019 PI3K and p38 act in a hierarchical manner to enhance mTORC1 activity and stress granule formation; although PI3K is the main driver, the impact of p38 gets apparent as PI3K activity declines.
Alexander Martin Heberle +12 more
doaj +1 more source
Assessing the microstructural and rheological changes induced by food additives on potato puree [PDF]
, 2018 The effects of agar, alginate, lecithin and glycerol on the rheological properties of commercial potato puree were investigated and interpreted in terms of starch microstructural changes, and the applicability of the Cox-Merz rule was evaluated.
Dankar, Iman +4 more
core +2 more sources
, 2020 The capacity of cells to organize complex biochemical reactions in intracellular space is a fundamental organizational principle of life. Key to this organization is the compartmentalization of the cytoplasm into distinct organelles, which is frequently achieved through intracellular membranes.
Min-Seok, Song, Elda, Grabocka
openaire +3 more sources
The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. [PDF]
, 2015 Previously, we identified ISRIB as a potent inhibitor of the integrated stress response (ISR) and showed that ISRIB makes cells resistant to the effects of eIF2α phosphorylation and enhances long-term memory in rodents (Sidrauski et al., 2013).
Ingolia, Nicholas T +3 more
core +2 more sources
A Phasin with Many Faces: Structural Insights on PhaP from Azotobacter sp. FA8 [PDF]
, 2014 Phasins are a group of proteins associated to granules of polyhydroxyalkanoates (PHAs). Apart from their structural role as part of the PHA granule cover, different structural and regulatory functions have been found associated to many of them, and ...
Bucci, Hernán Andrés +5 more
core +6 more sources
Regulated protein aggregation: stress granules and neurodegeneration
Molecular Neurodegeneration, 2012 The protein aggregation that occurs in neurodegenerative diseases is classically thought to occur as an undesirable, nonfunctional byproduct of protein misfolding. This model contrasts with the biology of RNA binding proteins, many of which are linked to
Wolozin Benjamin
doaj +1 more source
Rheology, granule growth and granule strength: Application to the wet granulation of lactose–MCC mixtures [PDF]
, 2011 This study aims at better understanding the wet granulation process of a binary mixture composed of microcrystalline cellulose (water insoluble) and lactose (water soluble).
Chitu, Toma Mihai +2 more
core +3 more sources
Using small-angle X-ray scattering to investigate the compaction behaviour of a granulated clay [PDF]
, 2015 The compaction behaviour of a commercial granulated clay (magnesium aluminium smectite, gMgSm) was investigated using macroscopic pressure-density measurements, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray microtomography (XμT) and ...
Aguzzi +59 more
core +1 more source
Stress Granules and Virus Replication [PDF]
Future Virology, 2011 Viruses are dependent on the cellular translation machinery for protein synthesis. Part of the innate immune response to infection is activation of the stress kinase PKR which phosphorylates the alpha subunit of the initiation factor eIF2. This results in inhibition of translation and is intended to block virus replication.
openaire +2 more sources