Results 121 to 130 of about 3,973,918 (385)

Shear jamming and fragility in dense suspensions [PDF]

open access: yesGranul. Matter, 21(3):82, 2019, 2019
The phenomenon of shear-induced jamming is a factor in the complex rheological behavior of dense suspensions. Such shear-jammed states are fragile, i.e., they are not stable against applied stresses that are incompatible with the stress imposed to create them.
arxiv   +1 more source

Stress granules dynamics: benefits in cancer

open access: yesBMB Reports, 2022
Stress granules (SGs) are stress-induced subcellular compartments, which carry out a particular function to cope with stress. These granules protect cells from stress-related damage and cell death through dynamic sequestration of numerous ribonucleoproteins (RNPs) and signaling proteins, thereby promoting cell survival under both physiological and ...
Jeong In Lee, Sim Namkoong
openaire   +2 more sources

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao   +4 more
wiley   +1 more source

Pesticides DEET, fipronil and maneb induce stress granule assembly and translation arrest in neuronal cells

open access: yesBiochemistry and Biophysics Reports, 2021
Pesticides entering our body, either directly or indirectly, are known to increase the risk of developing neurodegenerative disorders. The pesticide-induced animal models of Parkinson's disease and Alzheimer's disease recapitulates many of the ...
Pratibha Bhadauriya   +2 more
doaj  

Small-scale dynamo simulations: Magnetic field amplification in exploding granules and the role of deep and shallow recirculation [PDF]

open access: yes, 2018
We analyze recent high resolution photospheric small-scale dynamo simulations that were computed with the MURaM radiative MHD code. We focus the analysis on newly forming downflow lanes in exploding granules since they show how weakly magnetized regions in the photosphere (center of granules) evolve into strongly magnetized regions (downflow lanes). We
arxiv   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron   +3 more
wiley   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

open access: yesAdvanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André   +3 more
wiley   +1 more source

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection [PDF]

open access: yes, 2012
Dynamic, mRNA-containing stress granules (SGs) form in the cytoplasm of cells under environmental stresses, including viral infection. Many viruses appear to employ mechanisms to disrupt the formation of SGs on their mRNAs, suggesting that they represent
Eng, Kai Er   +6 more
core   +1 more source

P-body and Stress Granule Quantification in Caenorhabditis elegans

open access: yesBio-Protocol, 2017
Eukaryotic cells contain various types of cytoplasmic, non-membrane bound ribonucleoprotein (RNP) granules that consist of non-translating mRNAs and a versatile set of associated proteins. One prominent type of RNP granules is Processing bodies (P bodies)
Matthias Rieckher   +1 more
doaj   +1 more source

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