Results 61 to 70 of about 4,058,220 (323)
Development of a novel light-up probe for detection of G-quadruplexes in stress granules
Scientific Reports, 2022 G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up probe with
Keisuke Iida +4 more
doaj +1 more source
Biomolecular phase separation in stress granule assembly and virus infection
Acta Biochimica et Biophysica Sinica, 2023 Liquid-liquid phase separation (LLPS) has emerged as a crucial mechanism for cellular compartmentalization. One prominent example of this is the stress granule.
Liu Yi +3 more
doaj +1 more source
Plant stress granules and mRNA processing bodies are distinct from heat stress granules [PDF]
The Plant Journal, 2008 SummarySimilar to the situation in mammalian cells and yeast, messenger ribonucleo protein (mRNP) homeostasis in plant cells depends on rapid transitions between three functional states, i.e. translated mRNPs in polysomes, stored mRNPs and mRNPs under degradation.
Christian, Weber +2 more
openaire +2 more sources
Stress Granules in the Post-transcriptional Regulation of Immune Cells
Frontiers in Cell and Developmental Biology, 2021 Immune cell activation triggers transcriptional and translational programs eliciting cellular processes, such as differentiation or proliferation, essential for an efficient immune response.
Nicolas Curdy +18 more
doaj +1 more source
Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
eLife, 2020 RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm.
Chih-Yung S Lee +5 more
doaj +1 more source
Cells, 2022 Cells possess membraneless ribonucleoprotein (RNP) granules, including stress granules, processing bodies, Cajal bodies, or paraspeckles, that play physiological or pathological roles.
Pureum Jeon +3 more
doaj +1 more source
Viral modulation of stress granules
Virus Research, 2012 Following viral infection, the host responds by mounting a robust anti-viral response with the aim of creating an unfavorable environment for viral replication. As a countermeasure, viruses have elaborated mechanisms to subvert the host response in order to maintain viral protein synthesis and production.
Valiente-Echeverría, Fernando +2 more
openaire +2 more sources
Stress granules, P-bodies and cancer [PDF]
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2015 Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize post-transcriptional control mechanisms to re-program gene expression in ways that enhance cell survival. Stress granules and processing bodies are RNA-containing granules that contribute to this process by modulating cellular signaling pathways, metabolic ...
Paul, Anderson +2 more
openaire +2 more sources
Detecting Stress Granules in Drosophila Neurons [PDF]
, 2022 Stress granules (SGs) are cytoplasmic ribonucleoprotein condensates that dynamically and reversibly assemble in response to stress. They are thought to contribute to the adaptive stress response by storing translationally inactive mRNAs as well as signaling molecules.
de Graeve, Fabienne +6 more
openaire +3 more sources
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage
Journal of Cell Biology, 2022 Lysosomal damage induces stress granule (SG) formation and translational reprograming. The newly appreciated process of atg8ylation affects SG formation and concomitantly recruits SG core proteins NUFIP2 and G3BP1 to damaged lysosomes.
Jingyue Jia +12 more
semanticscholar +1 more source