Results 51 to 60 of about 2,813,474 (315)
Plant Stress Granules: Trends and Beyond [PDF]
Frontiers in Plant Science, 2021 Stress granules (SGs) are dynamic membrane-less condensates transiently assembled through liquid–liquid phase separation (LLPS) in response to stress. SGs display a biphasic architecture constituted of core and shell phases. The core is a conserved SG fraction fundamental for its assembly and consists primarily of proteins with intrinsically disordered
Maruri Lopez, Israel +3 more
openaire +4 more sources
Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
eLife, 2020 RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm.
Chih-Yung S Lee +5 more
doaj +1 more source
Biomolecular phase separation in stress granule assembly and virus infection
Acta Biochimica et Biophysica Sinica, 2023 Liquid-liquid phase separation (LLPS) has emerged as a crucial mechanism for cellular compartmentalization. One prominent example of this is the stress granule.
Liu Yi +3 more
doaj +1 more source
Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly [PDF]
Advanced Science, EarlyView.LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang +6 more
openalex +2 more sources
Kinetics of permeability changes induced by electric impulses in chromaffin granules [PDF]
, 1977 Lindner P, Neumann E, Rosenheck K. Kinetics of permeability changes induced by electric impulses in chromaffin granules. Journal of Membrane Biology. 1977;32(1):231-254.Electric field pulses, ranging in intensity from 20 to 50 kV/cm and in duration from ...
Lindner, P. +2 more
core +1 more source
A switch for stress granule assembly [PDF]
Journal of Cell Biology, 2016 ![Figure][1] Cells overexpressing USP10 (green) fail to form stress granules (magenta) when translation initiation is inhibited. [Kedersha et al.][2] describe how phosphorylation and the competition between mutually exclusive binding partners regulate G3BP’s ability to mediate ...
openaire +2 more sources
The Journal of Cell Biology, 2004 Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one
Sandqvist, Anton, Sistonen, Lea
openaire +2 more sources
Cells, 2022 Cells possess membraneless ribonucleoprotein (RNP) granules, including stress granules, processing bodies, Cajal bodies, or paraspeckles, that play physiological or pathological roles.
Pureum Jeon +3 more
doaj +1 more source
eLife, 2015 RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein aggregates or through phase separation into a liquid RNA/protein phase. Which model describes RNP granules in living cells is still unclear.
Sonja Kroschwald +7 more
doaj +1 more source
Shigella flexnerimodulates stress granule composition and inhibits stress granule aggregation [PDF]
Cellular Microbiology, 2016 Invasion and multiplication of the facultative, cytosolic, enteropathogen Shigella flexneri within the colonic epithelial lining leads to an acute inflammatory response, fever and diarrhea. During the inflammatory process, infected cells are subjected to numerous stresses including heat, oxidative stress and genotoxic stress.
Vonaesch Pascale +4 more
openaire +3 more sources