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Editorial: Biology of Stress Granules in Plants
Frontiers in Plant Science, 2022 Eukaryotic cells have developed sophisticated mechanisms to survive under ever-changing environments which include compartmentalization of translationally arrested mRNA molecules and proteins into a type of membraneless cytoplasmic foci called stress granules (SGs).
Monika Chodasiewicz +3 more
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Frontiers in Molecular Biosciences, 2022 Stress granules are non-membrane bound RNA-protein granules essential for survival during acute cellular stress. TIA-1 is a key protein in the formation of stress granules that undergoes liquid-liquid phase separation by association with specific RNAs ...
Danella L. West +7 more
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Plant Stress Granules: Trends and Beyond [PDF]
Frontiers in Plant Science, 2021 Stress granules (SGs) are dynamic membrane-less condensates transiently assembled through liquid–liquid phase separation (LLPS) in response to stress. SGs display a biphasic architecture constituted of core and shell phases. The core is a conserved SG fraction fundamental for its assembly and consists primarily of proteins with intrinsically disordered
Maruri Lopez, Israel +3 more
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Development of a novel light-up probe for detection of G-quadruplexes in stress granules
Scientific Reports, 2022 G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up probe with
Keisuke Iida +4 more
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Biomolecular phase separation in stress granule assembly and virus infection
Acta Biochimica et Biophysica Sinica, 2023 Liquid-liquid phase separation (LLPS) has emerged as a crucial mechanism for cellular compartmentalization. One prominent example of this is the stress granule.
Liu Yi +3 more
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Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
eLife, 2020 RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm.
Chih-Yung S Lee +5 more
doaj +1 more source
Les granules de stress, des acteurs émergents en cancérologie
, 2021 International audienceLes stress induits au sein des tumeurs en cours de développement (hypoxie, stress oxydant, etc.) sont connus depuis de nombreuses années.
Pauline Chavrier +5 more
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A switch for stress granule assembly [PDF]
Journal of Cell Biology, 2016 ![Figure][1] Cells overexpressing USP10 (green) fail to form stress granules (magenta) when translation initiation is inhibited. [Kedersha et al.][2] describe how phosphorylation and the competition between mutually exclusive binding partners regulate G3BP’s ability to mediate ...
openaire +2 more sources
Cells, 2022 Cells possess membraneless ribonucleoprotein (RNP) granules, including stress granules, processing bodies, Cajal bodies, or paraspeckles, that play physiological or pathological roles.
Pureum Jeon +3 more
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eLife, 2015 RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein aggregates or through phase separation into a liquid RNA/protein phase. Which model describes RNP granules in living cells is still unclear.
Sonja Kroschwald +7 more
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