Results 71 to 80 of about 1,437,569 (357)

Fracture study of windshield glass panes [PDF]

open access: yes
The major stresses which cause crack propagation in windshield glass panes are induced by bending moments which result from the pressure differentials across the panes.
Yeh, H. Y.
core   +1 more source

A Continuum Theory of Crack Shielding in Ceramics [PDF]

open access: yes, 1987
A phenomenological constitutive model is proposed which aims at describing the overall effect of microfracture in ceramics. Based on this model, the asymptotic stress, strain, and displacement fields at the tip of a stationary macroscopic crack are ...
Ortiz, M.
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Effect of debond growth on stress-intensity factors in a cracked orthotropic sheet stiffened by a semi-infinite orthotropic sheet [PDF]

open access: yes
Stress-intensity factors are determined for a cracked infinite sheet adhesively bonded to a stringer, and debonding of the adhesive layer is predicted. The stringer is modeled as a semi-infinite sheet. Adhesive nonlinearity is also included.
Bigelow, C. A.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Characterization of the stress-strain state in a gas turbine engine compressor disc taking into account damage accumulation

open access: yesFracture and Structural Integrity, 2019
A stress-strain state analysis of a gas turbine engine compressor disc was conducted with consideration to the accumulation of damages under various loading conditions in the temperature range.
Natalia Boychenko, Ivan Ishtyryakov
doaj   +1 more source

Studying the Effect of Pulse Shape on Dynamic Stress Intensity Factor at the Finite Crack Tip using Displacement Fields [PDF]

open access: yesInternational Journal of Advanced Design and Manufacturing Technology, 2020
In analytical studies, step (Heaviside) function is used to simulate an impact load. However, in real behaviour of materials, loading and unloading take a short time.
Hossein Rahmani   +1 more
doaj  

The effect of broken stringers on the stress intensity factor for a uniformly stiffened sheet containing a crack [PDF]

open access: yes
A linear elastic stress analysis was made of a centrally cracked sheet stiffened by riveted, uniformly spaced and sized stringers. The stress intensity factor for the sheet and the load concentration factor for the most highly loaded stringer were ...
Poe, C. C., Jr.
core   +1 more source

A Simplified Evaluation Method of the Stress Intensity Factor of a Circumferential Crack in a Cylinder Subjected to Axisymmetric Loads [PDF]

open access: yes, 1997
A simplified method to approximately evaluate the stress intensity factor of an arbitrarily located circumferential crack in a cylinder subjected to axisymmetric loads was theoretically derived, based on the theory of cylindrical shell and compliance ...
渡邊, 勝彦, 飯井, 俊行
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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