Results 141 to 150 of about 141,474 (306)
Epilepsia Open, EarlyView.Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Epilepsia Open, EarlyView.Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Ictal emotional features in pediatric and young adult patients with frontal lobe epilepsy
Epilepsia Open, EarlyView.Abstract Objective To assess the localization and lateralization values of ictal emotional features and ictal defensive behaviors in pediatric and young adult patients with frontal lobe epilepsy (FLE). Methods Children and young adults with FLE were identified from a single institution's epilepsy surgery database.
Ming‐Chen Tsai +6 more
wiley +1 more source
THE EFFECT OF DRUGS ON THE HOMOVANILLIC ACID CONTENT OF THE CORPUS STRIATUM OF SOME RODENTS [PDF]
, 1966 A. V. Juorio, D.F. Sharman, T Trajkov
openalex +1 more source
Selective Deletion of NBCe1 in Reactive Astrocytes Attenuates Ischemic Stroke Brain Damage
Glia, EarlyView.NBCe1 is upregulated in reactive astrocytes following ischemic stroke. Deletion of astrocytic Nbce1 reduces stroke volume, preserves AQP4 polarization, reduces BBB permeability, and improves neurological function after ischemic stroke. ABSTRACT The electrogenic sodium bicarbonate transporter 1 (NBCe1/Slc4a4), predominantly expressed in astrocytes, is ...
Okan Capuk +16 more
wiley +1 more source
Modification of Monoaminergic Activity by MAO Inhibitors Influences Methamphetamine Actions
Drug Target Insights, 2006 Methamphetamine (METH) abuse is a serious health and social problem worldwide. At present, however, there are no effective medications for the treatment of METH abuse.
Junichi Kitanaka +2 more
doaj
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
HELICAL FILAMENTS IN ASTROCYTIC MITOCHONDRIA OF THE CORPUS STRIATUM IN THE RAT [PDF]
, 1964 Enrico Mugnaini
openalex +1 more source
Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source