Results 41 to 50 of about 325,395 (379)

The dynamics of striatum circuitry [PDF]

open access: yesFrontiers in Integrative Neuroscience, 2010
Learning new motor skills is an integral and essential part of our life. Remember the first time riding a bike or learning to ski? After a new skill is acquired, the once daunting task becomes effortless and automatic. How does our brain accomplish such a feat? Which brain systems are involved, and how? A recent article by Yin et al.
openaire   +4 more sources

Lesions of the dorsomedial striatum delay spatial learning and render cue­-based navigation inflexible in a water maze task in mice

open access: yesFrontiers in Behavioral Neuroscience, 2014
The dorsal striatum is involved in cue‐based navigation strategies and in the development of habits. It has been proposed that striatum‐dependent cued navigation competes with hippocampus‐dependent spatial navigation in some circumstances.
Anni Seungeun Lee   +3 more
doaj   +1 more source

Brain region and gene dosage-differential transcriptomic changes in Shank2-mutant mice

open access: yesFrontiers in Molecular Neuroscience, 2022
Shank2 is an abundant excitatory postsynaptic scaffolding protein that has been implicated in various neurodevelopmental and psychiatric disorders, including autism spectrum disorder (ASD), intellectual disability, attention-deficit/hyperactivity ...
Ye-Eun Yoo   +4 more
doaj   +1 more source

Black-box and surrogate optimization for tuning spiking neural models of striatum plasticity

open access: yesFrontiers in Neuroinformatics, 2022
The basal ganglia (BG) is a brain structure that has long been proposed to play an essential role in action selection, and theoretical models of spiking neurons have tried to explain how the BG solves this problem.
Nicolás C. Cruz   +5 more
doaj   +1 more source

Maladaptive bias for extrahippocampal navigation strategies in aging humans. [PDF]

open access: yes, 2013
Efficient spatial navigation requires not only accurate spatial knowledge but also the selection of appropriate strategies. Using a novel paradigm that allowed us to distinguish between beacon, associative cue, and place strategies, we investigated the ...
de Condappa, Olivier   +3 more
core   +1 more source

The Striatum and Pain Modulation

open access: yesCellular and Molecular Neurobiology, 2011
The aim of this review was to give a general aspect of the sensorial function of the striatum related to pain modulation, which was intensively studied in our laboratory. We analyse the effect of electrical and chemical stimulation of the striatum on the orofacial pain, especially that produced by tooth pulp stimulation of the lower incisors.
Barcelo, Ana Cristina   +2 more
openaire   +4 more sources

The effects of melatonin on the striatum

open access: yesMarmara Medical Journal, 2021
Objective: Some of the neurological diseases cause morphologic changes in the striatal neurons. Medial forebrain bundle (MFB)lesion is a commonly used method to produce a Parkinsonian model rat. Melatonin is a hormone which exerts a neuroprotectiveeffect on the neurons.
GERGIN, Sinem   +4 more
openaire   +5 more sources

How the brain regulates alcohol intake

open access: yeseLife, 2022
A neural pathway involved in goal-oriented behaviours becomes dysregulated during binge drinking and alcohol use disorder.
Leigh C Walker   +2 more
doaj   +1 more source

Contributions of Reward Sensitivity to Ventral Striatum Activity Across Adolescence and Early Adulthood

open access: yesChild Development, 2018
It was examined how ventral striatum responses to rewards develop across adolescence and early adulthood and how individual differences in state‐ and trait‐level reward sensitivity are related to these changes.
E. Schreuders   +5 more
semanticscholar   +1 more source

Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

open access: yeseLife, 2016
Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice.
William Menegas   +3 more
semanticscholar   +1 more source

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