Results 41 to 50 of about 141,474 (306)
Frontiers in Neural Circuits, 2017 Basal ganglia circuit is an important subcortical system of the brain thought to be responsible for reward-based learning. Striatum, the largest nucleus of the basal ganglia, serves as an input port that maps cortical information. Microanatomical studies
Sabyasachi Shivkumar +2 more
doaj +1 more source
Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]
, 2018 The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro +7 more
core +3 more sources
Decreased dopamine activity predicts relapse in methamphetamine abusers. [PDF]
, 2012 Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the extent to which striatal DA function in METH predicts recovery has not been evaluated.
Alia-Klein, N +11 more
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Frontiers in Neuroscience, 2022 Hearing loss is a chronic health condition that affects millions of people worldwide. In addition to age-related hearing impairment, excessive noise exposure is a leading cause of hearing loss. Beyond the devastating effects of hearing impairment itself,
Salonee V. Patel +6 more
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Automatic cell segmentation by adaptive thresholding (ACSAT) for large-scale calcium imaging datasets [PDF]
, 2018 Advances in calcium imaging have made it possible to record from an increasingly larger number of neurons simultaneously. Neuroscientists can now routinely image hundreds to thousands of individual neurons.
Gritton, Howard J. +6 more
core +1 more source
, 2020 Published as part of Anisimov, N. S. & Bezborodov, V. G., 2020, Longicorn Beetles (Coleoptera, Cerambycidae) Of The Amur-Zeya Interfluve (Amurskaya Oblast, Russia), pp. 138-157 in Amurian Zoological Journal XII (2) on page 148, DOI: 10.33910/2686-9519-2020-12-2-138-157, http://zenodo.org/record ...
Anisimov, N. S., Bezborodov, V. G.
openaire +2 more sources
Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model
Frontiers in Neuroscience, 2017 Objective: Motor neurons (MNs) die in amyotrophic lateral sclerosis (ALS), a clinically heterogeneous neurodegenerative disease of unknown etiology. In human or rodent studies, MN loss is preceded by increased excitability.
Matthew J. Fogarty +5 more
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Frontiers in Cellular Neuroscience, 2020 In the striatum, the input nucleus of the basal ganglia, the extracellular-signal-regulated kinase (ERK) pathway, necessary for various forms of behavioral plasticity, is triggered by the combined engagement of dopamine D1 and ionotropic glutamate ...
Ilaria Morella +5 more
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Genetic tagging of the adenosine A2A receptor reveals its heterogeneous expression in brain regions
Frontiers in Neuroanatomy, 2022 The adenosine A2A receptor (A2AR), a G protein-coupled receptor, is involved in numerous and varied physiological and pathological processes, including inflammation, immune responses, blood flow, and neurotransmission.
Muran Wang +13 more
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Frontiers in Behavioral Neuroscience, 2022 Previous evidence indicates a link between early life stress (ELS) in humans and a predisposition to psychopathologies that are characterized in part by maladaptive habitual behaviors.
Ty M. Gadberry +2 more
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