Results 71 to 80 of about 325,395 (379)

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

A case of catheter related bloodstream infection by Corynebacterium striatum

IDCases, 2020
Background: C. striatum is an innocuous inhabitant of the normal human epithelial and mucosal surfaces. The C. striatum´s thogenic potential is increasingly recognized in our time. Methods: We present a rare case of CRBSI by C.
Yanmei Ge, Jingchuan Lu, Shaozun Feng, Wenli Ji, Huacheng Tong   +4 more
doaj  

Mapping neural circuits with CLARITY

eLife, 2015
The use of whole-brain imaging has shed new light on the organization of the dopamine system.
Amanda M Willard , Aryn H Gittis
doaj   +1 more source

Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates [PDF]

, 2016
Phosphodiesterase 10A (PDE10A) inhibitors show therapeutic effects for diseases with striatal pathology. PET radiotracers have been developed to quantify in vivo PDE10A levels and target engagement for therapeutic interventions. The aim of this study was
Alagille, David, Flores, Hubert, Han, Junbin, Jin, Hongjun, Liu, Hui, Perlmutter, Joel S, Su, Yi, Tamagnan, Gilles, Tu, Zhude, Yang, Hao, Yue, Xuyi   +10 more
core   +2 more sources

Antipsychotic treatment and functional connectivity of the striatum in first-episode schizophrenia.

JAMA psychiatry, 2015
IMPORTANCE Previous evidence has implicated corticostriatal abnormalities in the pathophysiology of psychosis. Although the striatum is the primary target of all efficacious antipsychotics, the relationship between its functional connectivity and ...
Deepak K. Sarpal, D. Robinson, T. Lencz, M. Argyelan, T. Ikuta, K. Karlsgodt, J. Gallego, J. Kane, P. Szeszko, A. Malhotra   +9 more
semanticscholar   +1 more source

Dopamine signaling in the striatum

, 2019
The striatum integrates dopamine-mediated reward signals to generate appropriate behavior in response to glutamate-mediated sensory cues. Such associative learning relies on enduring neural plasticity in striatal GABAergic spiny projection neurons which, when altered, can lead to the development of a wide variety of pathological states.
Valjent, Emmanuel, Biever, Anne, Gangarossa, Giuseppe, Puighermanal, Emma   +3 more
openaire   +5 more sources

Advances in Photonic Materials and Integrated Devices for Smart and Digital Healthcare: Bridging the Gap Between Materials and Systems

Advanced Materials, EarlyView.
This article summarizes significant technological advancements in materials, photonic devices, and bio‐interfaced systems, which demonstrate successful applications for impacting human healthcare via improved therapies, advanced diagnostics, and on‐skin health monitoring.
Seunghyeb Ban, Hoon Yi, Jaejin Park, Yunuo Huang, Ki Jun Yu, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Age and gender effects on striatal dopamine transporter density and cerebral perfusion in individuals with non-degenerative parkinsonism: a dual-phase 18F-FP-CIT PET study

EJNMMI Research
Background Dual-phase fluorine-18 labeled N-3-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) scans could be used to support disorders like Parkinson’s disease (PD).
Ji-Young Kim, Seo Young Kang, Byung Seok Moon, Bom Sahn Kim, Jee Hyang Jeong, Hai-Jeon Yoon   +5 more
doaj   +1 more source

Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis

eLife, 2014
Synaptic transmission between midbrain dopamine neurons and target neurons in the striatum is essential for the selection and reinforcement of movements. Recent evidence indicates that nigrostriatal dopamine neurons inhibit striatal projection neurons by
Nicolas X Tritsch, Won-Jong Oh, Chenghua Gu, Bernardo L Sabatini   +3 more
doaj   +1 more source

White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology

Frontiers in Molecular Neuroscience, 2022
IntroductionAn inactivating mutation in the histidine decarboxylase gene (Hdc) has been identified as a rare but high-penetrance genetic cause of Tourette syndrome (TS). TS is a neurodevelopmental syndrome characterized by recurrent motor and vocal tics;
Kantiya Jindachomthong, Chengran Yang, Yuegao Huang, Daniel Coman, Maximiliano Rapanelli, Fahmeed Hyder, Fahmeed Hyder, Joseph Dougherty, Luciana Frick, Christopher Pittenger, Christopher Pittenger, Christopher Pittenger, Christopher Pittenger   +12 more
doaj   +1 more source