Results 71 to 80 of about 257,053 (199)

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

open access: yesAdvanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang   +11 more
wiley   +1 more source

One-loop monodromy relations on single cuts

open access: yesJournal of High Energy Physics, 2017
The discovery of colour-kinematic duality has led to significant progress in the computation of scattering amplitudes in quantum field theories. At tree level, the origin of the duality can be traced back to the monodromies of open-string amplitudes ...
Alexander Ochirov   +2 more
doaj   +1 more source

Aspects of holographic string theory [PDF]

open access: yes, 2009
In this thesis we study several aspects of gauge/gravity dualities. We start by analyzing the structure of the UV divergences of the Wilson loop for a general gauge/gravity duality.
Giataganas, Dimitrios   +1 more
core  

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

open access: yesAdvanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo   +6 more
wiley   +1 more source

Duality symmetries in string theory

open access: yes, 1996
We review recent progress in our understanding of duality symmetries in string ...
Sen, Ashoke, Ashoke Sen
core   +1 more source

Eleven-dimensional origin of string/string duality: a one-loop test [PDF]

open access: yes, 1995
Membrane/ fivebrane duality in D = 11 implies Type IIA string/Type IIA fivebrane duality in D = 10, which in turn implies Type HA string/heterotic string duality in D = 6. To test the conjecture, we reproduce the corrections to the 3-form field equations
DUFF, MJ, LIU, JT, MINASIAN, R
core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang   +8 more
wiley   +1 more source

Towards generalized mirror symmetry for twisted connected sum G 2 manifolds

open access: yesJournal of High Energy Physics, 2018
We revisit our construction of mirror symmetries for compactifications of Type II superstrings on twisted connected sum G 2 manifolds. For a given G 2 manifold, we discuss evidence for the existence of mirror symmetries of two kinds: one is an ...
Andreas P. Braun, Michele Del Zotto
doaj   +1 more source

Spacetime supersymmetry and duality in string theory [PDF]

open access: yes, 1995
I discuss the role of spacetime supersymmetry in the interplay between strong/weak coupling duality and target space duality in string theory which arises in string/string duality.
Khuri, Ramzi R.
core  

Putting string/fivebrane duality to the test [PDF]

open access: yes, 1992
According to string/fivebrane duality, the Green-Schwarz factorization of the $D=10$ spacetime anomaly polynomial $I_{12}$ into $X_4\, X_8$ means that just as $X_4$ is the anomaly polynomial of the $d=2$ string worldsheet so $X_8$ should be the anomaly ...
Duff, M.J.   +5 more
core   +1 more source

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